From: 
Sukie Crandall 
Date: 2001-04-07 13:19:00 UTC
Subject: what we noticed here in relation to darkness and light
             Our living situation:
Housing is excessively expensive around here and is in most areas 
where Steve could work at his chosen specialty, so we have a small 
condo and can not devote a room just to the ferrets the way we would 
like to do, due to lack of space.  They do get a large amount of 
"out" time -- about 12 to 14 hours every 24,  typically.
They have lighting in daytime hours and black window curtains, plus 
black cage covering for night that exclude most light (Gets very 
black in there.); when they also get into the bedding it's likely 
that pretty well all light is excluded.
What we have seen:  we are still having adrenal neoplasias develop, 
but have not seen any adrenal malignancies since the use of the 
covers.
Interestingly, years ago we saw very few adrenal growths.  Now, early 
on (We've had ferrets for around 19 years.) the vets didn't tend to 
recognize adrenal growths, anyway.  Still, even taking that into 
account there HAS been a very real change over the years at least in 
our household.  Adrenal neoplasias have become more common and just 
this last year we are actually seeing them earlier --in middle age 
rather than old age. Adrenal malignancies have not been seen here 
since the night covers.  I don't know if any of that reflects any 
actual change or just some random clumping; family groups simply are 
not large enough to permit hard conclusions, even despite other 
aspects that present interpretation difficulties.  Meanwhile, we have 
also personally encountered less lympho in recent years, which also 
may mean squat.  It's pretty well impossible to tell anything 
conclusive from a small sample.
There are a number of research articles that exist on levels of 
natural melatonin production (from light exclusion) and how having 
enough darkness appears to be able to reduce rates of hormonally 
related malignancies in humans and in rodents.  The line of inquiry 
began largely because it was noticed that blind people with certain 
forms of blindness had lower levels of some hormonal cancers.  There 
was a large article a few years back in Science News which did a 
wonderful review of most of the related studies at that time; it may 
be at their website.
I have heard form others who have also noticed a trend toward adrenal 
neoplasias  happening earlier, but do not know how much of that is 
coincidence.