From: Bruce Williams, DVM
Date: 2001-04-21 15:12:00 UTC
Subject: Re: Follow up Mackenzie's insulinoma surgery
> Okay, I thought this might come up, so when I consented for the
> specimens to go to the pathologist I asked if I would be able to
> them back in case I wanted a second opinion, and I was told yes.
> on Monday or tuesday I will call my vet and ask if I can get the
> parafin blocks. Are there specific things I should ask for? Or
> parafin blocks?
The paraffin blocks are what is needed, or a set of 10 recuts from
each block, so that I can run a series of tests - insulin, keratin,
and probably others.
> By the way, out of curiosity, if the mets are not islet cell
> carcinoma and are another type of adenocarcinoma as you suggested,
> what else is in the differential diagnosis?
Gastric, intestinal, even adrenal would probably be in the
differential. However, many of the carcinomas which spread widely in
the abdomen, are too anaplastic (immature) to identify a definitive
cell of origin until necropsy.
With kindest regards,
Bruce H. Williams, DVM, DACVP
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