From: 
Bruce Williams, DVM 
Date: 2001-05-02 15:00:00 UTC
Subject: Re: conjested heart failure
             --- In Ferret-Health-list@y..., "Psalm 366" <psalm36_6@h...> wrote:
> I woke up this past Saturday to see my ferret very weak. The trip 
to the vet 
> showed fluid around the heart. She now is on Lasix and Enacard. Has 
anyone 
> gone this route with a ferret? She is 1 of age. Can anyone tell me 
how long 
> they have seen ferrets live on this medication?
Debora - you may want to check the archives for information on 
cardiomyopathy.  This is a disease in which heart muscle is replaced 
by scar tissue, and the heart is then unable to effectively pump the 
blood throughout the body.  Lasix is a diuretic prescribed to 
decreased the blood volume and make it easier to pump it around the 
body, and Enacard relaxes the blood vessels to make themwider and 
easire to pump the blood through.  The third component of therapy 
which will eventually enter the picture is digoxin, a digitalis 
derivative which strengthens the contraction and normalizes the 
rhythm of a failing heart.
Cardiomyopathy is a common problem in American ferrets, with a likely 
genetic background.  However, when it is seen in a 1-year-old, it is 
a poor prognostic sign.  Many old ferrets have some signs of it at 
necropsy, but are claimed by other diseases first.
One thing to remember is that we cannot cure cardiomyopathy, only 
slow its inevitable progression.  Medication and response should be 
monitored carefully, and dosages optimized as best as possible to 
prolong quality of life as long as possible.  While I am hesitant to 
handicap the lifespan of a young ferret with cardiomyopathy, for him 
to see his second birthday would mean that you have done extremely 
well managing his condition.
With kindest regards,
Bruce H. Williams, DVM, DACVP
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