From: 
Sukie Crandall 
Date: 2001-05-18 15:12:00 UTC
Subject: Re: Ferret coats and adrenal (was repeated passing of 
blood)
             >quite coarse of coat, and almost feels like there is some sort of
>coating on the hair. You can see the thinning hair pattern quite 
>clearly on Gizmo's back at 
>http://www.geocities.com/kourifanclub/SOS.html  Of course the 
>texture is less obvious in a photo, but I think adrenal ferrets feel 
>dirty.
Yes, sometimes they can feel dirty; we've also noticed that.  We have 
also noticed that the undercoats seems to usually be lost before the 
guard-hairs so the feeling is usually harsher.  In addition, I think 
that the changes to the skin that can happen (thinning, drying, 
wrinkling, pimpling) can give a different feel at times, and we know 
if someone with thick skin gets hurt a lot that we may be seeing 
thinner skin combined with rowdier behavior.
>
>Gizmo has a smell that I have come to associate
>as, "the adrenal smell." In fact all four of the shelter ferrets that
>currently need surgery are coarse of coat and smell like that. It's
>almost a medicinal/urine type smell and I've never smelled it on a
Have noticed that, too.  To us it smells more like a hormonal 
increase.  Differs from the sweet-rotty smell that can happen with 
malignancies.  When Meltdown had her sudden adrenal symptoms many 
years ago we wanted him to go in right away because she smelled 
sweet-rotty, and in her case it was a malignancy but caught so early 
that surgery was completely curative and she went on to have 3 and 
1/2 more years and eventually die in old age of a different problem 
(cardiomyopathy).
>
>also, handing me a ferret and saying.. see he's starting to smell
>adrenal.. so I'm not completely off my rocker.. at least one other
>person smells it. Anyone else experienced or noticed this?
Yes.
We have also found that a loss of normal smell gives a good 
assessment of health.  Ferrets which have smell (We had one years ago 
who was odorless who we had to supply with perfume for stink-status.) 
and then lose odor have typically had something serious going wrong, 
we've noticed, and recovery of smell is a good indicator of improving 
health.  Smell can be very useful in assessing them.