From: 
Bruce Williams, DVM 
Date: 2001-08-01 16:04:00 UTC
Subject: Re: Bilateral Adrenal
             --- In Ferret-Health-list@y..., katharine <shurcool@i...> wrote:
> >Dr. Williams mentioned in a post in March (see, I
> 
> > really did search the archives) that 25% will do
> 
> > fine on pred, 25% need pred and DOCP, and 50%
> > don't need anything.  How do you make this
> > determination?
> the determination is made on the  basis of clinical signs and lab 
work.  If the animal motors on without any problems after bilateral 
adrenal suregery - in such cases it is probably not a true bilateral 
removal, or the animal has abundant ectopic tissue - then it doesn't 
need any medication post op.  If the animal loses energy and crashes 
after surgery, and the bloodwork shows that it is hypoglycemic, 
prednisone alone may relieve the problems.  Some animals if they are 
part minority thatsecrete cortisol may have problems with 
hypoglycemia after surgery.  Prednsione is an effective agent for 
raising blood glucose.
Finally if the animal crashes up to a month out from surgery, and the 
Na:K ratio is abnormal - usually around 25, it suggests that the 
animal suffers from mineralocorticoid deplation, and DOCP is used to 
straighten out this electrolyte balance.
A close eye is reuqired in many cases to get the problems 
straightened out.
With kindest regards,
Bruce Williams, DVM, DACVP
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