Message Number: YG7120 | New FHL Archives Search
From: Mike Janke
Date: 2001-09-08 19:38:00 UTC
Subject: Re: Can anyone tell me how Melatonin works on adrenal.

If I may quote from an article by Jerry Murray, DVM...

"Melatonin is a natural hormone that is secreted by the pineal gland.
Melatonin is involved in activating (in the spring) and terminating
(in the fall) the ferret hypothalamic-pituitary-gonadal axis in
response to the seasonal changes in the photoperiod (amount of
daylight). Melatonin inhibits GnRH release,decreases LH and FSH, and
ultimately decreases the sex hormone concentrations."

Lupron, on the other hand, is a synthetic version GnRH (gonadotropin
release hormone). By supplying relatively high and constant levels
of GnRH to the pituitary, the pituitary is desensitized and
circulating LH and FSH are reduced or eliminated.

Adrenals respond to LH (luteinizing hormone) and FSH (follicle-
stimulating hormone)by [over]producing sex hormones.

Anyway, that's my take on it. It may not be related in a 100%
scientifically accurate manner, but it's a rough idea of what the
problem (usually) is and why Melatonin (and Lupron) work to relieve
the symptoms of adrenal disease.

Can't help you with fish antibiotics, but I sure wouldn't be giving
that stuff to my animals!


--- In Ferret-Health-list@y..., CFERRETTAILS@a... wrote:
> Hi,
> I have read that some people give Melatonin to ferrets that have
adrenal. I would like to know what Melatonin does for adrenal and
what the drug is.