From:
Jen & Andre
Date: 2001-11-28 10:58:00 UTC
Subject: inconclusive lab results, please help
I posted this a while back, but I thought I would repost it
in hopes that someone might be able to respond
Newton is slipping, she's getting weaker and sleeps almost all
of the time.
For more than a month I've been trying to find out what's
wrong with her, just to be told that everything is
inconclusive. After an ultrasound and a set of @ 15 slides
made from lymph node, spleen and liver aspirates (while under
anesthetic) the vets said it was inconclusive and would need a
biopsy (but the doctor who does biopsies wouldn't do a
ferret). That leaves going back for more aspirates.
The doctor thinks it's lymphoma, but she told me that yet
another doctor believes it is not (because only the largest
lymphocytes were abnormal, the small and medium ones were
normal). She says it could also be insulinoma that has spread
to other organs is this likely?
Newton was in for tests November 16
Here are her lab results:
(finished prednisone7-10 days ago- prior to the FNAs)
anemia, throbocytopenia, mild leukocytosis with left shift
serum biochem- mild azotemia (sp? messy handwriting), no
hypoglycemia as previously seen (it had been 3.6)
FNA enlarged LN, spleen, peripheral LN= reactive
lymphadenopathy? but some large blastic cells
Hepatic cept: inflammatory cells?
suspect neoplasia but FNA unable to confirm. inflammatory?
infection?
FNA of spleen, cyst in liver, R submandibular LN
Na 156 mmol/L urea 17.8 CK
64 U/L
K 5.5 creat. 78
AST [GOT] 36
Na:K 28 Glucose 4.1 ALT
[GPT] 70
Cl- 125 cholest. 4.9
Gamma-GT 67
Ca 2.59 T. bili 2 umol/L T.
prot. 77 g/L
P 3.35 Amylase 32 U/L albumin
23 g/l
globulin 54 g/L
A:G .43
lipase 451 U/L
SDH 4 U/L
WBC 9.1 X10E9/L WBC Diff. (%)
(X10E9/L) Plasma
RBC 5.80 X10E12/L Segs 40% 3.64
hemolysis
HBC 84 g/L Bands 6%
.54 turbidity:+
HCT .238 L/L
MCV 40.8 fL Eos 1%
.09
MCH 14.4pg Baso
protein: 82 g/L
MCHC 354 g/L Lymph 44%
4.00
RDW 18.7% Mono 9%
.81
PLTS 153 X10E9/L Disint
retics .1% (x10E9/L)
Pct 1.65
MPV 10.8 fL NRBC /100
WBC
PDW 16.8% toxic SLI
Corr. WBC
9.1 x10E9/L
C morphology:
isocytosis 1+
ikilocytosis 1+
enation/burr cells
If there's anything you can tell me from this, and the past
messages I've posted please let me know. If there's something
I can do for her I want to be able to do it. Newton's on
pred, but the doctor says if I want to do chemo to not give
pred. I Had her on baytril for a while to see if it was
infectious but there was no response.
Please help
Jen
ps, additional info: she's got a big spleen full of hypoechoic
holes, masses in her liver (one was aspirated, urine coloured
liquid, it was full of neutrophils), enlarged left adrenal,
thorax was opaque on rads, couldn't outline heart (opaqueness
didn't respond to diuretics), dorsal bend in trachea just
cranial to heart. arrhythmia was detected >3 weeks ago, but
normal now. She shows poor balance, hind end weakness (no
seizures), when rolled onto her back it puts her into fits of
heaves.