Message Number: SG1234 | New FHL Archives Search
From: williamsb@comcast.net
Date: 2002-09-03 13:27:44 UTC
Subject: RE: Megaesophagus
To: ferrethealth@smartgroups.com
Message-ID: <7460912.1031059664463.JavaMail.root@scandium>

Dear Julie -

Megaesophagus is still somewhat of a mystery disease in the feret. The distribution is primarily male, primary middle-aged to older, and there are currently no known triggers for it in ferrets, as opposed to dogs, wehre it may be realated to myasthenia gravis or conincidental to thymoma, a tumor of the thymus which shares some antigenic similarities to the acetylcholine receptors of the esophageal muscle (which causes the body to turn on the muscle as well).

Currently therapy is simply carful management, feeding of a slurry in most cases, and feeding from an elevated platform. I was under the impression that propulsid was unavailable on the market - how did you secure it.

Megaesophagus is generally a progressive disease with a poor prognosis. Most animal eventually succumb to aspiration pneumonia or ulceration and yeast infection of the esophagus, as it empties poorly into the stomach.

The definitive diagnosis is rather easy - a small amount of barium given by mouth will reveal a greatly dilated esophagus on X-ray.

With kindest regards,

Bruce Williams, DVM

Author wrote:
> We have not run any tests on Sammy to validate a
> diagnosis of Megaesophagus, but I believe that is what
> this little guy's problem is.
> He is a beautiful, robust little male now, growing in
> a silky new coat.
> Does anyone know if Mega-E is progressive or, if it is
> caught and dealt with, it's progression can be halted?
> Does anyone know what might be the cause of this
> condition to develop?
> Julie