From:
"Ferretlove"
Date: 2002-10-04 14:08:19 UTC
Subject: Mason's histopathology report (for Dr Williams)
To: "Ferret-Health-list" <ferrethealth@smartgroups.com>
Message-ID: <004501c26baf$9f4a7120$ce10ff3e@petestanley>
Dear Dr Williams
I had another word with my vet and she said that she did not give Mason any
glucose so the high blood glucose must have had another reason... My vet
also rang the laboratory for re-sectioning the liver and pancreas after
receiving the first histology report because she was sure that there were
tumours on both the pancreas and liver. I've included the second report.
This is the histopathology report:
Exotic histology
The liver has a normal architecture with scattered foci of mononuclear cells
within portal areas. Hepatocytes are moderately vacuolated. The pancreas
includes lobules of active acinar cells as well as several small nodular
structures formed from tall epithelial cells arranged in packets and nests.
The cells have oval nuclei and low mitotic activity. Similar cells are
scattered through the tissue associated with acinar cells. There is a
diffuse mixed inflammatory infiltrate. The third structure is composed of
irregular papillary processes and ducts lined by tall columnar epithelial
cells. The underlying tissues are infiltrated by lymphoid cells. Mixed
inflammatory cells are present within several ducts. The structure is
surrounded by fibromuscular tissue.
Comment
There is no evidence of a liver tumour in these sections. The liver is
showing only mild, non-specific degenerative changes. The pancreas includes
multiple nodules likely to represent a form of nodular hyperplasia. There
is mild pancreatitis. The third tissue is not lymph node although it
includes lymphoid cells. It is ductular and may be of biliary or other
origin. It is inflamed.
Further report
Further portions of the liver have been processed and within these there is
now evidence of multilocular cystic mass. The cysts are lined by attenuated
cuboidal epithelial cells with narrow fibrous septa. Adjacent to the cystic
area there is a solid area of small polygonal cell proliferation. These
cells have small oval nuclei and low mitotic activity. They are tending to
form small packets and ducts. There is a little fibroplasias and a mild
lymphoid infiltrate and foci of neutrophils. This is consistent with bile
duct cystic hyperplasia and adenoma formation. Further processing of tissue
from the pancreas also now includes several large irregular nodular masses
composed of ducts and solid aggregates of quite pleomorphic cells with
variable nuclei and moderate mitotic activity. There is local and vascular
invasion consistent with carcinoma formation.
Best wishes
Ulrike
West Wales Ferret Welfare
E-mail: ferretlove@ntlworld.com
http://www.ferretlove.co.uk (when it's back up)
http://homepage.ntlworld.com/ferretlove (in the meantime)
Last update 26/09/02
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