Message Number: SG2640 | New FHL Archives Search
From: Sukie Crandall
Date: 2002-12-19 01:47:11 UTC
Subject: viral precursor for some lympho cases (clumps)
To: ferrethealth@smartgroups.com
Message-Id: <a05200f0aba26d339dc1c@[10.0.1.40]>

I had some very kind sympathy notes. (Thank you for sending the ones
without health content to me privately.) My old server is glitchy and
I find that soem of my thank you notes to people in reply to their
sympathy notes are coming back to me. Please, forgive me if the
server does this; we are switchiing so are ina sort of netherworld
right now. I did try.)

Do remember that lymphoma can occur NOT in clumps, too, and the
likely viral precursor is for the clump situation.

Some of the notes asked for more info on lympho clumps and possible
viral precursors so i searched. I am sure that i have missed some
but these past FHL posts should help you:

http://fhl.sonic-weasel.org/browse.php?msg=YG12862

(last line)

>I will try to clear some of your confusion.
>Fromm-D was actually a chicken embryo cell culture vaccine.
>(This is very similar to the Fervac-D vaccine.)
>The newer version Galaxy-D is a simian (monkey) cell culture
>vaccine. No virus involved in either of these 2 vaccines.
>The new Merial Purevax-D is a recombinant vaccine
>using a canary pox virus as a carrier. They also use this
>canary pox vector in their dog vaccines. No vaccine connection
>to lymphoma, but there may be a ferret retro virus involved in
>lymphoma.
>Hope that helps,
>Jerry Murray, DVM

http://fhl.sonic-weasel.org/browse.php?msg=YG8921

> > We are among those who have had a lympho clump.
>>
>> The hypothesis that there might ba viral trigger for some cases
>> was investigated for a while at the Dept. of Comparative
>> Medicine of MIT, but they didn't find a culprit. That doesn't
>mean
>> that such a silent viral contributor doesn't exist; it is just a
>> reflection of how very difficult such studies are.
>>
>
>
>In the mid 90's, Sue Erdman published that lymphoma could be spread
>by a cell-free inoculum between an animal with lymphoma and a normal
>healthy one (actually 4/6 in this study developed. this is strong
>evidence that a virus in involved, as the filtering system used would
>also filter out bacteria.
>
>There are a number of animal species that have viruses that can cause
>lymphoma - with the most common culprits being retroviruses and
>herpesviruses.
>
>However, there was no success at isolating the virus, and when I most
>recently talked with Sue about six months ago, she is no longer
>investigating lymphoma in ferrets, so it is doubtful that fursther
>work along these lines is forthcoming from MIT. (This is not
>uncommon in the research world, as research is quite expensive, and
>today, only funded experiments go forward.
>
>Regarding the originl question about aspirating nodes - if the nodes
>are indeed enlarged, then an aspirate is always a good idea.
>Remember that fat often accumulates around the nodes of older
>ferrets, causing them to appear enlarged. However, an aspirate is a
>very safe, relatively painless procedure that can usually be done
>without general anesthesia.
>
>With kindest regards,
>
>Bruce Williams, dVM
>