Message Number: SG330 | New FHL Archives Search
Date: 2002-07-16 21:52:25 UTC
Subject: RE: [ferrethealth] RE: wild mink and ADV (NE US)?
Message-ID: <22644501.1026856345732.JavaMail.root@scandium>

Author wrote:
> (both of those Japanese studies refered to the cases as being
> spontaneous ones)
> You can't have spontaneous cases of ADV can you? They must mean long
> term carriers that went active?

That confused me as well when I saw the study summaries at Pub Med. Wish I had access to the actual studies.

On re-reading the first article may just refer to new strains being spontaneous but on the second it may not mean that. (I'm not at my best today.) Take a look at the summaries and see how you read them. Meanwhile, here are a few lines. Since one author may be the same I wonder if the 2000 ferret was one of the two in the 2001 paper?

>: J Vet Diagn Invest 2001 Jul;13(4):337-40

>Nucleotide sequence and polymerase chain reaction/restriction fragment length
>polymorphism analyses of Aleutian disease virus in ferrets in Japan.

>Murakami M, Matsuba C, Une Y, Nomura Y, Fujitani H.

>Laboratory of Molecular Biology, School of Veterinary Medicine, Azabu
>University, Sagamihara, Kanagawa, Japan.

>Two ferrets with spontaneous Aleutian disease (AD) were found in Japan. The
>diagnosis was verified by polymerase chain reaction (PCR) amplification of part
>of the capsid gene specific to AD virus (ADV).

>these isolates had 96% sequence similarity to a published ferret ADV (FADV)
>in contrast to <91% homology to various types of mink ADV (MADV).

>These results indicated that the 2 isolates found in Japan were new DNA types of FADV and could >have been derived from FADV(s).

>PMID: 11478607 [PubMed - indexed for MEDLINE]

>: J Vet Med Sci 2000 May;62(5):553-5

>Spontaneous Aleutian disease in a ferret.

>Une Y, Wakimoto Y, Nakano Y, Konishi M, Nomura Y.

>Department of Veterinary Pathology, School of Veterinary Medicine, Azabu
>University, Sagamihara, Kanagawa, Japan.

>A 3-year-old female ferret died five days after admission to a veterinary clinic
>On analysis of PCR products, using primers directed against the gene encoding Aleutian disease (AD) >viral capsid and formalin-fixed kidney samples, we detected a single band of about 400 bp, specific >to the AD virus.

PMID: 10852410 [PubMed - indexed for MEDLINE]