From:
GRNTEE@aol.com
Date: 2002-02-01 04:03:00 UTC
Subject: Bria and Dr Williams
Not sure if you remember, but about a week ago I posted about a
tumor that was removed from my ferrets ear. They had suggested to
me that it was a metasasis from her adrenal gland disease. You had
asked for the pathology report. I obtained it yesterday while at my
vets office. I also gave him information that you all helped me
with about insulinoma and we have Bria started on the appropriate
meds. Thanks everyone for that information. Here is the path
report.
GROSS DESCRIPTION: received fixed is one rubbery piece of brown
colored tissue measuring 1.4 x 0.9 x 0.6 in size. The tissue is
bisected and totally submitted.
HISTOPATHOLOGIC DIAGNOSIS:
Poorly idfferentiated, primarily solid carcinoma, possibly a
cutaneous metastases from an adrenal gland neoplasm, a biopsy of a
lesion from the left pinna.
MICROSCOPIC DESCRIPTION AND COMMENTS: four H & E stained pieces of
a lesion from the left pinna are evaluated. The skin architecture
has been almost completely effaced and replaced by a neoplastic
epithelial infiltrate. A portion of the pinnal cartilage is present
in one section. The tumor consists of primarily solid sheets and
islands of cells that are subdivided by a medium to dense fibrous
stroma. In some areas there is evidence of residual poor acinar
differentiation. These lobules frequently contain areas of central
necrosis. Focally extensive areas of acute hemorrhage and some
patchy inflammation are also noted. The tumor cells generally have
large round to ovoid, active-appearing nuclei comprised of
euchromatin and contain prominent large nucleoli. Individual tumor
cell degeneration is commonly seen. The mitotic rate ranges from 0
to 3/HPF. Although the lesion generally appears to be well
circumscribed, many of the margins are badly fragmented, and I
cannot provide an assurance of complete excision.
The microscopic findings are consistent with a very poorly
differentiated carcinoma. As this neoplasm is not typical in my
experience, of primary epithelial tumors of ferret skin, I am
concerned that it may indeed represent a cutaneous metastases from a
previously excised adrenal gland neoplasm (although this would be a
somewhat unusual metastatic location). The animal should be
monitored for the possible development of other foci of carcinoma.
(This is directly quoted from the pathology report. Conforming to
the rules of this board I am not sure as if I should post the
pathologist who reported this as I am quoting, but also know I am
not to mention the Dr's or pathologists names. Sukie, you may do as
you wish with this and if I need to report the author please let me
know and I will redo this report.)
Dr. Williams, I just want to thank you in advance for looking into
this for me. Sincerely, Tina McFeaters