From:
Ulrike Stanley
Date: 2002-03-28 13:26:00 UTC
Subject: Jack's Histopathology report
I was hoping that the report would explain why Jack had such an abnormal
build-up of fat in his body and chest but it doesn't. I was wondering
whether it was fat tumours. I'd like people/ vets to comment on the fat and
report and what they think...
Histopathology report
History
Difficulty breathing, very enlarged abdomen (6-10 months). Sudden
deterioration over last 24 hours. Euthanased. PM Fat, large amounts in
abdomen & chest especially around kidneys, also mesentery, bladder/uterus.
Diagnosis
Pancreatic Endocrine Tumour Insulinoma and Interstitial Pneumonia
Prognosis
Prognosis Not Given
Commentary
Spleen: There is marked splenic congestion and some haemorrhage. No
evidence of neoplasia.
Pancreas: There is a large well vascularised mass comprising cords and
packets of pleomophic polygonal cells with marked nuclear atypia and
variable fine cytoplasmic vacuolation.
Adipose tissue adjacent to pancreas and within mesentery: This contains
small accessory spleens and several small to large nodules (up to 1.5cm) of
neoplasia as described in the pancreas.
Heart: Normal.
Lungs: Congested and collapsed with accumulation of mixed inflammatory cells
within the interstitium.
Kidneys: Largely within normal and expected to have been functioning
antemortem.
COMMENTS:
The changes are consistent with a malignant tumour arising from islet cells
(insulinoma) with metastatic spread and an intersitial pneumonia. The cause
of the latter is not apparent from the histological features.
Jack's autopsy photos:
www.ferretlove.co.uk/jackpm.htm
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