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From: Caitlyn Martin
Date: Wed Jan 2, 2002 5:21pm
Subject: Re: [Ferret-Health-list] Bilateral adrenals: why
prednisone?

Hi, Roger, and everyone else,

> Dexamethasone is much stronger and has a much longer half-life - on the
> order of 3-4 days. It sticks around much longer, and daily doses will
> tend to accumulate more in the body than will pred.

This may explain why Pertwee and Ryo-Ohki benefit from dexamethasone.
Both have extremely high metabolisms. Both had to have their dosages
halved and given twice a day--otherwise they began to show serious
Addisonian symptoms.

To give you an idea how high a metabolism they have: Pertwee can run
for hours and hours. He can eat gravy by (literally) the bowl, eat
kibble, get Ferretvite as a treat, and we still have a hard time
maintaining his weight. My vet is having his thyroid function checked
again as a result. Ryo-Ohki is not quite as frenetic as Pertwee, but
she's a close second. These are my two highest energy wired weasels.

Anyway, I am curious to see what the vets have to say.

All the best,
Caity and the terrific 10


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