From:
Ferrethealer@aol.com
Date: 2003-01-12 02:37:44 UTC
Subject: Re: [ferrethealth] Digest 12 Jan 2003 02:13:53 -0000 Issue 202
To: ferrethealth@smartgroups.com
Message-ID: <95.286d0317.2b522ef8@aol.com>
In a message dated 01/11/03 9:14:18 PM Eastern Standard Time,
ferrethealth-digest-help@smartgroups.com writes:
> Can lupron lose it's effectiveness over time?
I don't think that it loses its effectiveness, but rather that the type of
adrenal problem shifts to one that is not responsive to Lupron. My own
ferret responded beautifully to Lupron for over a year, then stopped
responding. I reluctantly (she was quite frail) took her into surgery and
removed a golf ball sized mass that came back as histologically a very
malignant tumor.
My theory is that initially she had had hyperplasia which was responsive to
Lupron, but then developed the tumor.
I have seen this happen a couple of times since then, each time the mass
removed has been a fairly malignant one, I'm sorry to say.
Dr. Ruth
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