From:
FHbytheSea@aol.com
Date: 2003-01-14 13:13:08 UTC
Subject: Buster's aspirate results
To: ferrethealth@smartgroups.com
Message-ID: <fb.352e8950.2b5566e4@aol.com>
Finally have them back from the lab:
>Clinical information: Ferret 5 yo, neutered male. Owner reports low grade
wheeze and occ cough. CBC wnl. THoracic x-ray. Shows cardiac shadow wnl and
localized lung density involving middle lung lobe left side 1 x 0.5cm area of
condolidation with air bronchogram. Lesion nonresponsive to antibiotics.
Specimen information: fine needle aspirate thoracic in area of lesion, blind
FNA not U/S guided (middle lung, left side) 2 prestained and 1 air dried
slide sent.
Cytologic diagnosis:
Focal mass, left middle lung lobe: sparsely sampled lymphohistiocytic and
eosinphilic inflammation.
Cytologic description: A total of three overall sparsely cullular slides are
examined, demonstrating predominately individualized inflammatory self
contained in a modest background of erythrocytes and minimal proteinaceous
precipitates. The predominant cell appears to be an alveolar
macrophage/histiocyte demonstrating round to oval to reniform nuclei, modest
to abundant of pale slightly vacuolated cytoplasm, without obvious
intracytoplasmic infectious agents. Adminxed iwth the histiocytes are fewer
well-differentiated to occasionally immunoreactive lymphocytes and a modest
population of eosinphils. The eosinphils appear to be in excess for the
peripheral blood background and are not admixed with significant numbers of
neutrophils. There is a rare group of well differentiated epithelial cells,
representing small columnar cells without cytological criteria of dysplasia
or malignancy. Obvious infectious agents or neoplastic infiltrates are not
identified.
Comments: Clinical history indicates wheezing and occasional cough in this
ferret. Thoracic radiographs demonstrate a localized lung density involving
the left middle lung lobe approximately 1 x 0.5cm. This lesion has been
nonresponsive to antibiotics. Aspiration has yeilded a mixed
lymphohistiocytic and eosinphilic inflammatory process unassociated with an
obvious etiological agent or a neoplastic infiltrate. The eosinphilic
component of this inflammation suggests the possibility of a
hypersensitivity/allergic or parasitic etiology, though occasionally,
eosinphilic inflammation can also be associated with bacterial and fungal
infections and some neoplasms. THe inflammation does not include a
significant purulent response that would suggest a bacterial component or
abundant tissue necrosis, though should be correlated with additional
clinicopathological data.>
So what this is saying is that the spot on his lung is possibly an allergic
reaction to something? He is currently on prednisolone 2x a day...
Any ideas?
Lisa Leidig, Head Ferret
The Ferret Haven "By-the-Sea"
www.ferrethaven.org