From:
Betty
Date: 2003-02-20 19:22:31 UTC
Subject: Cirrhosis of the Liver addendum
To: "ferrethealth@smartgroups.com" <ferrethealth@smartgroups.com>
Message-id: <3E552AEE.F2D561A6@shaw.ca>
Gadget's lab report stated this:
"Sections of the liver reveal marked derangement of architecture in
which the liver tissue is subdivided into poorly organized nodules by
bands of inflamed collapsed parenchyma and or scar tissue. The
infiltrates are composed of macrophagea, lymphocytes, plasma cells and
fewer neutrophils. There is lymphocytic hyperplasia in portal areas.
Some nodules are fatty and there are occasional nodules of regenerative
liver tissue. Scattered within the inflammation are macrophages laden
with hemosiderin. Sections of the adrenal gland reveal enlargement of
the gland associated with nodular hyperplasia of the cortical cells. The
cells involved appear to be derived from the zona fasciculata and or
reticularis. There is a prominent infiltrate of lymphocytes.
Cirrhosis, Benign nodular Adrenocortical hyperplasia
The microscopic findings in the liver are consistent with chronic end
stage liver disease. At this stage it is not possible to identify a
cause. Liver failure if not already present is probably eminent. Out of
curiosity, special stains for copper and iron were done. There is
abundant copper present and iron is also increased but it is limited to
Kupffer cells consistent with sequestration. Sequestration can be seen
with cholestasis and chronic inflammation, both of which are present in
this case. Hyperplastic or neoplastic proliferative changes in the
adrenal gland or glands is common in ferrets. The excess secretion of
hormone is thought to be the basis for symmetrical alopecia noted
clinically."
betty and her blur o'fur
for the love of ferrets