From:
"Roger Vaughn"
Date: 2003-06-25 01:58:09 UTC
Subject: Follow Up- Lymphoma report and treatments
To: <ferrethealth@smartgroups.com>
Message-ID: <3753.192.168.132.34.1056506289.squirrel@mail.seaconinc.com>
Here are excerpts from the pathology report for Guinevere (re: Adult
Lymphoma). As mentioned before, she's asymptomatic so far - this was
found by very alert vets. Does this sound like we should be
considering chemo yet? My understanding from the reading I have done
is no, we should not, and this might in fact be a hyperplastic rather
than neoplastic node. I don't mean to gainsay a pathologist by any
means, but if I'm reading Fox correctly, hyperplasia is easily
mistaken for lymphoma. [Fox 2ed. pp 238-9] As far as Gwinny is
concerned, it may be a purely academic distinction anyway.
"Examined are two sections of lymph nodes. One lesion is being
effaced by a neoplastic proliferation of small mature
well-differentiated lymphocytes. These are effacing the normal
architecture and filling the subcapsular sinus, extending out into the
surrounding adipose tissue. The lymphocytes are small, mature, and
well differentiated, and the mitotic rate is low at 1-2 per high power
field. The other lymph node section has prominent primary and
secondary follicle formations. There is an increased proliferation of
small mature well-differentiated lymphocytes in the subcapsular sinus
although it is not completely effaced at this time... This ferret does
have a neoplastic lesion (lymphosarcoma) in one of the lymph node
biopsy sections... This resembles the gastrointestinal lymphosarcomas
of ferrets associated with Helicobacter mustelae."
Thanks for any advice.
roger & the wolverine wannabees
missing bear and lancelot
End of ferrethealth Digest
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