Message Number: SG6558 | New FHL Archives SearchFrom: "Sue Liszewski"
Date: Fri, 07 Nov 2003 11:38:18 -0600
To: ferrethealth@smartgroups.com
Subject: Re: [ferrethealth] Transdermal Flagyl
Message-ID: <LAW12-F99y15jfXX9u90000b2e6@hotmail.com>
The pharmacists I have spoken with have said that they can't make it
accurately anyway. The molecules in antibiotics are far too large to get a
proper dosing with this medication and thus won't do it anyway.
>From: mjanke@miamiferret.org
>Reply-To: ferrethealth@smartgroups.com
>To: ferrethealth@smartgroups.com
>Subject: [ferrethealth] Transdermal Flagyl
>Date: Fri, 7 Nov 2003 13:22:49 +0000 (GMT)
>
>From a post to the FHL when it was back on Yahoo Groups...
>
>
>From: Bruce Williams, DVM
>Date: Sun Nov 25, 2001 11:03pm
>Subject: Re: Flagyl
>
>--- In Ferret-Health-list@y..., "Coppandco" <Coppandco@h...> wrote:
> > I have just found a wonderful way to get that "hated" antibiotic
>Flagyl. My vet has given me Flagyl in a topical cream. You just rub
>a measured amount onto the skin and then just let it work. Of course
>it helps that this particular ferret - Okisi - is bald (he never grew
>back his hair after his last adrenal surgery). The Flagyl appears to
>be working well and for once I have absolutely no problems in
>administering it.
> > I would be interested in hearing from anyone else who has used this
>method, especially any pros and cons.
>
>Dear Rena:
>
>I have serious concerns about the use of transdermal Flagyl. I have
>discussed this with otehr vets on this list, as well as pharmacists.
>Metronidazole is used in ferrets for treatment of two agents - one a
>bacteria (Helicobacter) and one a protozoan (Giardia). Both of these
>agents are extracellular and live in the lumen of the stomach and
>intestine, respectively.
>
>As these agents live outside the tissues of the body, in the space
>within the gut, we rely on oral administration to get the proper
>dosage of the antibiotic to these pathogens. When you administer it
>with a cream, you get a low blood level of the antibiotic, which
>likely does not get into the lumen of the gut at all, and is probably
>of no effect.
>
>Metronidazole creams are effective in human females for vaginal
>infections, in which it is deposited into the vagina where it can be
>effective against some pathogens, but is not used in that form for GI
>problems.
>
>With kindest regards,
>
>Bruce Williams, dVM
>
>
>
>
>
>
>
>--
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>visit http://www.smartgroups.com/groups/ferrethealth
>
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