From:
"Ulrike"
Date: 2003-12-10 17:19:42 UTC
Subject: Help with histopathology report, please...
To: "Ferrethealth" <ferrethealth@smartgroups.com>
Message-Id: <3FD755AE.000005.03700@Ferretlove1>
My Baby had an operation last Thursday, I wrote about it a few days ago. =
She is about 7 1/2 years old, neutered. Pictures of her operation are on
page
www.ferretlove.co.uk/babyop.htm
I am just worried that nothing was wrong with her at all and I put her
through a big operation for nothing... The report does not make much sense=
to me...
Ulrike
=
Histopathology report
=
History
=
1.Sudden appearance tumour L inguinal, ? lymph node. Off food, lost weight=
.=
Cut surface necrosed. 2. Ex lap =96 all internal organs NAD. Cystic tum=
our
small curvature of stomach, aspirated fluid.
=
Diagnosis
=
Cellulitis and Purulent Lymphadenitis
=
Prognosis
=
Prognosis: Uncertain =96 Aetiology Not Clarified In This Submission
=
Commentary
=
The submission consists of a biopsy sample of skin and subcutis, including
mass, from the inguinal area, plus a fluid sample from which two smears wer=
e
made, for cytology.
=
HISTOPATHOLOGY: the sections reveal the mass is a lymph node embedded in
subcutaneous adipose tissue. The latter is heavily infiltrated by mixed
inflammatory cells, with a high proportion of neutrophils, and the
inflammation extends into the lymph node, which is also rather haemorrhagic=
,
but shows little cortical follicular activity. There is no overt evidence
of neoplasia in the sections examined. There is mild hyperplasia of mammar=
y
gland elements in the dermis overlying the inflamed node, and although ther=
e
is some inflammation within the gland, the pattern is not that of a true
mastitis, more of a bystander effect.
=
The appearances are consistent with focally severe, sub-acute cellulites
with associated purulent lymphadenitis. The cause could not be identified
in the sections, but is presumed to be bacterial infection. =
=
CYTOLOGY: the smears are about 50% erythrocytes and 50% nucleated cells, bu=
t unfortunately, for some reason, the latter are poorly preserved and the m=
ajority difficult to identify. Most are small, round cells about 1-1.5x th=
e diameter of an erythrocyte and I suspect they are lymphoid. This would s=
uggest the mass is either a hyperplastic lymph node, or a lymphoma. The la=
ck of cellular detail in the smears, however, means I am unfortunately unab=
le to make a firm diagnosis.