From:
mjanke@miamiferret.org
Date: 2004-11-19 00:29:39 UTC
Subject: RE: 2 questions on Lupron
To: ferrethealth@smartgroups.com
Message-ID: <2868899.1100824179909.JavaMail.root@thallium.smartgroups.com>
Author wrote:
> If we start Cookie tomorrow with a 100 mcg dose (1 month depot)and there's no effect after 1 month ... We'll have to increase the dosage to 200, 300, 400, and than to 500 mcg.
It's true that 100 mcg may not be effective. It seems unlikely that you'd have to go up that many steps to find an effective dose, but that is certainly possible. It's even possible that no amount of Lupron will be effective.
What I'd do (and have done), is go with the lower dose first. If that doesn't work, skip the 200 mcg dose and go right to 300.
> Dr Weiss says that the most effective dose is 500 mcg, and lower doses don't reverse the symptoms ...
500 mcg would almost certainly be effective in all cases where Lupron is going to work. I don't believe he has ever said that lower doses don't work. Keep in mind that much of the things he has written about Lupron is from 4 to 5 years ago. Lupron usage was not nearly as common back then as it is now and I think a lot has been learned about it in that time. One of the things we've learned is that doses much smaller than 500 mcg can be very effective!
> Question # 2
> I've read and some people told me that their vet give one shot of Lupron and waits until the symptoms come back to give a new one ...
> I know that Lupron dosages can last longer ... but what do you think of this approach ?
I wholeheartedly disagree with this approach. If it's one-month Lupron, give it once a month. four-month Lupron, every four months.
mike