Message Number: SG7606 | New FHL Archives Search
Date: 2004-01-28 03:32:21 UTC
Subject: vasopressin for vasodilatory shock
Message-ID: <>

Has anyone run into veterinary use in ferrets of vasopressin for vasodilatory shock (such as can happen when the muscles around the arterioles don't contract properly so blood pressure drops with sepsis, with prolonged shock of other causes, etc.) in ferrets? In humans it can raise the blood pressure when Epi and some other things no longer work (apparently by allowing norepinephrine to open calcium channels in the surrounding muscle, reducing nitric oxide levels which at times can be raised too much by inflammation, etc.)

There is a great little (5 page) article on it in the February Sci Am, and two articles are cited in "Circulation" ( Vol. 95, No. 5, pages 1122-1125; March 4 1997, and in "New Eng. J. of Medicine" Vol. 345, No. 8, Pages 588-595; Auguest 23, 2001 with the primary authors being Donald W. Landry and Juan A. Oliver.

BTW, how would one categorize anaphylactic shock? It seems to have components of both vasodilatory shock and hypovolemic (low blood volume) shock.

End of ferrethealth Digest