From:
sukiec@optonline.net
Date: 2005-04-05 22:05:10 UTC
Subject: RE: air cleaners: making sure they don''t damage lungs
To: ferrethealth@smartgroups.com
Message-ID: <7552221.1112738710842.JavaMail.root@thallium.smartgroups.com>
Someone privately asked about studies of tobacco smoke and ferrets. I replied:
Studies of the effects of tobacco smoke on ferrets? Oh, gosh, just go to Pubmed or its Hubmed version and you will find a LOT. There are also others which can be found with a Google search, and I am such some will come up when looking in places like NIMH, CDC, USDA, etc. There are ones listed in the FML Archives, too, because I know that both Bob Church and I have referred to such studies in the past.
In Pubmed
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
searching on
ferret tobacco
gets
1:
Liu C, Lian F, Smith DE, Russell RM, Wang XD.
Related Articles, Links
Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets.
Cancer Res. 2003 Jun 15;63(12):3138-44.
PMID: 12810641 [PubMed - indexed for MEDLINE]
2:
Liu C, Russell RM, Wang XD.
Related Articles, Links
Exposing ferrets to cigarette smoke and a pharmacological dose of beta-carotene supplementation enhance in vitro retinoic acid catabolism in lungs via induction of cytochrome P450 enzymes.
J Nutr. 2003 Jan;133(1):173-9.
PMID: 12514286 [PubMed - indexed for MEDLINE]
3:
Wolf G.
Related Articles, Links
The effect of beta-carotene on lung and skin carcinogenesis.
Carcinogenesis. 2002 Aug;23(8):1263-5.
PMID: 12151342 [PubMed - indexed for MEDLINE]
4:
Wolf G.
Related Articles, Links
The effect of low and high doses of beta-carotene and exposure to cigarette smoke on the lungs of ferrets.
Nutr Rev. 2002 Mar;60(3):88-90. Review.
PMID: 11908745 [PubMed - indexed for MEDLINE]
5:
Liu C, Wang XD, Bronson RT, Smith DE, Krinsky NI, Russell RM.
Related Articles, Links
Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets.
Carcinogenesis. 2000 Dec;21(12):2245-53.
PMID: 11133814 [PubMed - indexed for MEDLINE]
6:
Wang XD, Liu C, Bronson RT, Smith DE, Krinsky NI, Russell M.
Related Articles, Links
Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke.
J Natl Cancer Inst. 1999 Jan 6;91(1):60-6.
PMID: 9890171 [PubMed - indexed for MEDLINE]
7:
Lotan R.
Related Articles, Links
Lung cancer promotion by beta-carotene and tobacco smoke: relationship to suppression of retinoic acid receptor-beta and increased activator protein-1?
J Natl Cancer Inst. 1999 Jan 6;91(1):7-9. No abstract available.
PMID: 9890162 [PubMed - indexed for MEDLINE]
8:
Sindhu RK, Rasmussen RE, Kikkawa Y.
Related Articles, Links
Exposure to environmental tobacco smoke results in an increased production of (+)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide in juvenile ferret lung homogenates.
J Toxicol Environ Health. 1996 Apr 19;47(6):523-34.
PMID: 8614021 [PubMed - indexed for MEDLINE]
9:
Sindhu RK, Rasmussen RE, Kikkawa Y.
Related Articles, Links
Effect of environmental tobacco smoke on the metabolism of (-)-trans-benzo[a]pyrene-7,8-dihydrodiol in juvenile ferret lung and liver.
J Toxicol Environ Health. 1995 Aug;45(4):453-64.
PMID: 7643432 [PubMed - indexed for MEDLINE]
10:
Sindhu RK, Rasmussen RE, Yamamoto R, Fujita I, Kikkawa Y.
Related Articles, Links
Depression of hepatic cytochrome P450 monooxygenases after chronic environmental tobacco smoke exposure of young ferrets.
Toxicol Lett. 1995 Apr;76(3):227-38.
PMID: 7762009 [PubMed - indexed for MEDLINE]
11:
Rasmussen RE, Mannix RC, Oldham MJ, Phalen RF.
Related Articles, Links
Effects of nitrogen dioxide on respiratory tract clearance in the ferret.
J Toxicol Environ Health. 1994 Jan;41(1):109-20.
PMID: 8277524 [PubMed - indexed for MEDLINE]
while
ferret smoke
gets:
Liu C, Russell RM, Wang XD.
Related Articles, Links
Low dose beta-carotene supplementation of ferrets attenuates smoke-induced lung phosphorylation of JNK, p38 MAPK, and p53 proteins.
J Nutr. 2004 Oct;134(10):2705-10.
PMID: 15465770 [PubMed - indexed for MEDLINE]
2:
Liu C, Russell RM, Wang XD.
Related Articles, Links
Alpha-tocopherol and ascorbic acid decrease the production of beta-apo-carotenals and increase the formation of retinoids from beta-carotene in the lung tissues of cigarette smoke-exposed ferrets in vitro.
J Nutr. 2004 Feb;134(2):426-30.
PMID: 14747683 [PubMed - indexed for MEDLINE]
3:
Russell RM.
Related Articles, Links
The enigma of beta-carotene in carcinogenesis: what can be learned from animal studies.
J Nutr. 2004 Jan;134(1):262S-268S. Review.
PMID: 14704331 [PubMed - indexed for MEDLINE]
4:
Liu C, Lian F, Smith DE, Russell RM, Wang XD.
Related Articles, Links
Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets.
Cancer Res. 2003 Jun 15;63(12):3138-44.
PMID: 12810641 [PubMed - indexed for MEDLINE]
5:
Liu C, Russell RM, Wang XD.
Related Articles, Links
Exposing ferrets to cigarette smoke and a pharmacological dose of beta-carotene supplementation enhance in vitro retinoic acid catabolism in lungs via induction of cytochrome P450 enzymes.
J Nutr. 2003 Jan;133(1):173-9.
PMID: 12514286 [PubMed - indexed for MEDLINE]
6:
Wolf G.
Related Articles, Links
The effect of beta-carotene on lung and skin carcinogenesis.
Carcinogenesis. 2002 Aug;23(8):1263-5.
PMID: 12151342 [PubMed - indexed for MEDLINE]
7:
Wolf G.
Related Articles, Links
The effect of low and high doses of beta-carotene and exposure to cigarette smoke on the lungs of ferrets.
Nutr Rev. 2002 Mar;60(3):88-90. Review.
PMID: 11908745 [PubMed - indexed for MEDLINE]
8:
Liu C, Wang XD, Bronson RT, Smith DE, Krinsky NI, Russell RM.
Related Articles, Links
Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets.
Carcinogenesis. 2000 Dec;21(12):2245-53.
PMID: 11133814 [PubMed - indexed for MEDLINE]
9:
Wang XD, Liu C, Bronson RT, Smith DE, Krinsky NI, Russell M.
Related Articles, Links
Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke.
J Natl Cancer Inst. 1999 Jan 6;91(1):60-6.
PMID: 9890171 [PubMed - indexed for MEDLINE]
10:
Lotan R.
Related Articles, Links
Lung cancer promotion by beta-carotene and tobacco smoke: relationship to suppression of retinoic acid receptor-beta and increased activator protein-1?
J Natl Cancer Inst. 1999 Jan 6;91(1):7-9. No abstract available.
PMID: 9890162 [PubMed - indexed for MEDLINE]
11:
Sindhu RK, Rasmussen RE, Kikkawa Y.
Related Articles, Links
Exposure to environmental tobacco smoke results in an increased production of (+)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide in juvenile ferret lung homogenates.
J Toxicol Environ Health. 1996 Apr 19;47(6):523-34.
PMID: 8614021 [PubMed - indexed for MEDLINE]
12:
Sindhu RK, Rasmussen RE, Kikkawa Y.
Related Articles, Links
Effect of environmental tobacco smoke on the metabolism of (-)-trans-benzo[a]pyrene-7,8-dihydrodiol in juvenile ferret lung and liver.
J Toxicol Environ Health. 1995 Aug;45(4):453-64.
PMID: 7643432 [PubMed - indexed for MEDLINE]
13:
Sindhu RK, Rasmussen RE, Yamamoto R, Fujita I, Kikkawa Y.
Related Articles, Links
Depression of hepatic cytochrome P450 monooxygenases after chronic environmental tobacco smoke exposure of young ferrets.
Toxicol Lett. 1995 Apr;76(3):227-38.
PMID: 7762009 [PubMed - indexed for MEDLINE]
14:
Rasmussen RE, Mannix RC, Oldham MJ, Phalen RF.
Related Articles, Links
Effects of nitrogen dioxide on respiratory tract clearance in the ferret.
J Toxicol Environ Health. 1994 Jan;41(1):109-20.
PMID: 8277524 [PubMed - indexed for MEDLINE]
15:
Nadel JA.
Related Articles, Links
Neutral endopeptidase modulation of neurogenic inflammation in airways.
Eur Respir J Suppl. 1990 Dec;12:645s-651s. Review.
PMID: 2076158 [PubMed - indexed for MEDLINE]
I suspect that breaking down the components of cigarette smoke, from nicotene, to formaldehyde, to... and searching on those could also be useful for finding more.