Message Number: SG15337 | New FHL Archives SearchFrom: sukiec@optonline.net
Date: Fri, 9 Sep 2005 15:39:12 +0100 (BST)
To: ferrethealth@smartgroups.com
Subject: RE: Biaxin, Dilated Cardiomyopathy & Possible Kidney Disease
Message-ID: <7594646.1126276752594.JavaMail.root@thallium.smartgroups.com>
Author wrote:
> Well, the Carafate mixed with a bit of baby food worked for a little whil=
e
For complete effect you really do not want to give the Carafate with food.
Ask the vet for a prescription for the liquid prep of Carafate that any pha=
rmacy (and now some vets) carry. A large number of ferrets are good about =
accepting that, the amounts needed are small, and it works fast. Then don'=
t feed right away. Give the med time to settle over the damaged stomach ar=
eas. =
Do not give other oral meds for at least a half hour on either side of givi=
ng the Carafate, preferably longer. We usually have at least an hour on ou=
r medication times chart here between Carafate and any other med.
Have you asked your vet and pharmacist about possible conflicts for the med=
s in relation to both the diseases diagnosed and the medications given for =
those diseases? =
(Okay, I am searching about the Biaxin and so far have not found your answe=
r, but I DID find an intriguing mention of chronic Mycoplasma or Chlamydia =
infections in the companion animals of some Gulf War veterans which have sy=
mptoms that worsen if treated with penicillin but which respond to Biaxin a=
nd some other things:
http://www.immed.org/illness/veterinary_testing.html =
Also, not what you are seeking but intriguing: a page of newly tried drugs=
and drug combos for use in vet med for a wide range of conditions:
http://www.vetmed.auburn.edu/index.pl/whatsnew )
Potentially interesting note when dealing with an inflammatory disease (fro=
m a study of induced Pseudomonas sepsis in the kidneys of rabbits in =
Antimicrob Agents Chemother. 2004 January; 48(1): 93=969 :
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3D310186
START QUOTE
Clarithromycin is a macrolide classically known to possess an antimicrobial=
spectrum that includes gram-positive cocci and atypical pathogens (23). Ho=
wever, an increasing body of evidence suggests that clarithromycin possesse=
s considerable anti-inflammatory and immunomodulatory properties, recommend=
ing its administration for the treatment of chronic inflammatory conditions=
like diffuse panbronchiolitis and cystic fibrosis (11, 21, 26). Its immuno=
modulatory properties are observed in vitro at concentrations close to 10 ?=
g/ml (14). On the basis of that finding, intravenous administration of clar=
ithromycin leading to the same levels in blood might be beneficial for the =
treatment of an acute inflammatory state like sepsis.
END QUOTE
This is for humans, but it looks like it might have the data you seek:
http://www.rxlist.com/cgi/generic/clarith_ad.htm
I don't have the skim a pdf (because I can't have highlighters inserted in =
those by using a "cached" option in Google, but this may be useful:
http://www.usp.org/pdf/EN/veterinary/macrolides.pdf
The following is on optimizing antibacterial therapy:
http://www.vetmed.auburn.edu/index.pl/antimicrobial
=
=
End of ferrethealth Digest
***********************************
Send comments to Pam at pjdutche@email.unc.edu. Please note that this address is only useful for questions about the FHL archive. Questions about ferret health, or those intended for the FHL, should be sent to the Ferret Health List.