From:
sukiec@optonline.net
Date: 2005-09-09 14:39:12 UTC
Subject: RE: Biaxin, Dilated Cardiomyopathy & Possible Kidney Disease
To: ferrethealth@smartgroups.com
Message-ID: <7594646.1126276752594.JavaMail.root@thallium.smartgroups.com>
Author wrote:
> Well, the Carafate mixed with a bit of baby food worked for a little whil=
e
For complete effect you really do not want to give the Carafate with food.
Ask the vet for a prescription for the liquid prep of Carafate that any pha=
rmacy (and now some vets) carry. A large number of ferrets are good about =
accepting that, the amounts needed are small, and it works fast. Then don'=
t feed right away. Give the med time to settle over the damaged stomach ar=
eas. =
Do not give other oral meds for at least a half hour on either side of givi=
ng the Carafate, preferably longer. We usually have at least an hour on ou=
r medication times chart here between Carafate and any other med.
Have you asked your vet and pharmacist about possible conflicts for the med=
s in relation to both the diseases diagnosed and the medications given for =
those diseases? =
(Okay, I am searching about the Biaxin and so far have not found your answe=
r, but I DID find an intriguing mention of chronic Mycoplasma or Chlamydia =
infections in the companion animals of some Gulf War veterans which have sy=
mptoms that worsen if treated with penicillin but which respond to Biaxin a=
nd some other things:
http://www.immed.org/illness/veterinary_testing.html =
Also, not what you are seeking but intriguing: a page of newly tried drugs=
and drug combos for use in vet med for a wide range of conditions:
http://www.vetmed.auburn.edu/index.pl/whatsnew )
Potentially interesting note when dealing with an inflammatory disease (fro=
m a study of induced Pseudomonas sepsis in the kidneys of rabbits in =
Antimicrob Agents Chemother. 2004 January; 48(1): 93=969 :
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3D310186
START QUOTE
Clarithromycin is a macrolide classically known to possess an antimicrobial=
spectrum that includes gram-positive cocci and atypical pathogens (23). Ho=
wever, an increasing body of evidence suggests that clarithromycin possesse=
s considerable anti-inflammatory and immunomodulatory properties, recommend=
ing its administration for the treatment of chronic inflammatory conditions=
like diffuse panbronchiolitis and cystic fibrosis (11, 21, 26). Its immuno=
modulatory properties are observed in vitro at concentrations close to 10 ?=
g/ml (14). On the basis of that finding, intravenous administration of clar=
ithromycin leading to the same levels in blood might be beneficial for the =
treatment of an acute inflammatory state like sepsis.
END QUOTE
This is for humans, but it looks like it might have the data you seek:
http://www.rxlist.com/cgi/generic/clarith_ad.htm
I don't have the skim a pdf (because I can't have highlighters inserted in =
those by using a "cached" option in Google, but this may be useful:
http://www.usp.org/pdf/EN/veterinary/macrolides.pdf
The following is on optimizing antibacterial therapy:
http://www.vetmed.auburn.edu/index.pl/antimicrobial
=
=
End of ferrethealth Digest
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