Message Number: SG15827 | New FHL Archives Search
From: AFERRETVET@cs.com
Date: 2005-10-29 00:00:40 UTC
Subject: [ferrethealth] Re:Arimidex and Casodex
To: ferrethealth@smartgroups.com

Hi Volker,
Anemia in ferrets with adrenal gland disease is
a result of the high estrogen levels. Therefore to treat
anemia from adrenal gland disease, you must lower
the estrogen level. This can be done with several medications,
and in cases with severe anemia several medications should
be used together. Lupron is the first medication. It stops the
stimulation to the adrenal gland(s), so the adrenal gland(s)
produces less estrogen. Arimidex is an aromatase inhibitor,
so it stops the production of estrogen from estrogen precursors
and prevents other hormones (such as DHEAS, ANDRO, and
TESTOSTERONE) from being converted to estrogen. Melatonin
also stops the stimulation to the adrenal gland, can work as an
aromatase inhibitor, AND stimulates the bone marrow to produce
red blood cells. Epogen and Procrit also stimulate the bone marrow
to make more red blood cells. Pet tinic can be used too. This liquid
supplements iron and B vitamins to help the bone marrow make more
red blood cells.
Casodex is not used for estrogen induced bone marrow toxicity.
Casodex is a receptor blocker for androgen (DHT) receptors. It is
used primarily in cases of male ferrets with prostate problems,
and in case with return of sexual behavior or aggressive behavior.
If the andro level is really elevated in a female ferret, it may help
some, but it is used mostly in male ferrets.
Hope that clears things up,
Jerry Murray, DVM




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