From:
Sukie Crandall
Date: 2006-03-26 20:45:37 UTC
Subject: [ferrethealth] Purevax
To: FHL <ferrethealth@smartgroups.com>
http://66.70.134.35/recommendations_for_merial.htm
includes:
> Merial's new PUREVAX (tm) Ferret Distemper Vaccine which is now on
> the market, is a univalent, lyophilized product of a recombinant
> canary pox vector expressing canine distemper virus antigens. The
> vaccine cannot cause canine distemper under any circumstances and
> its safety and immunogenicity have been demonstrated by vaccination
> and challenge tests in susceptible ferrets. Pet ferrets appear to
> be susceptible to post-vaccinal hypersensitivity reactions however,
> and a low incidence (0.3%) of reversible anaphylactic reactions
> occurred in field safety trials carried out by Merial.
>
> The same vaccine was provided by Merial under a special USDA permit
> to the AAZV Distemper Vaccine Subcommittee (via Dr. Dick Montali)
> for field trials at zoos and wildlife facilities between 1997-2001.
> The vaccine was used mostly for animals housed outside with a risk
> of exposure to canine distemper. Species vaccinated included giant
> pandas, red pandas, raccoons, coatis, cacomistles, maned wolves,
> channel island foxes, fennec foxes, cusimanses, otters, lions,
> tigers, pumas, cheetahs and clouded leopards. In general,
> immunogenicity appeared to be favorable with some intraspecific
> variations and no untoward local or systemic reactions.
So, notice that the zoo vaccine is the same one as the ferret
vaccine. Which means that if they stop packaging as ferret vaccine
it should be possible to use the zoo vaccine, though dose adjustment
may be needed. (I thought that this vaccine was also used on seals
which also get CD. Yes, many of the big cats get CD; that is not an
error. Also cusimanses are small viverrids -- a short tailed type of
mongoose with a very small range -- that actually are said to tame
easily and make excellent pets. Ferrets are mustelids.)
Merial still has Purevax listed among its products at
http://merialusa.naccvp.com/prodlist.php?mannum=1111&u=country&p=msds
-- Sukie (not a vet)
Ferret Health List co-moderator
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