From:
sukiec@optonline.net
Date: 2006-04-18 20:42:54 UTC
Subject: [ferrethealth] RE: Dr. Jerry Murray has approved this post: adrenal disease cause no longer a hypothesis but now PROVEN
To: ferrethealth@smartgroups.com
Remember from 3 decades ago that the Monkees performed a perceptive Neil Diamond song, "A Little Bit Me, A Little Bit You"?
Well, I can't get the chorus out of my head today and here is why.
In relation to adrenal disease formation the scenario goes like this:
Decreased complete darkness results in decreased melatonin production from the pineal gland.
Decreased melatonin production (less melatonin circulating) results in more LH and FSH production from the pituitary.
Now, if all goes right and if the ferret has reproductive tissue intact the reproductive tissue at some point sends a "Quiet down." signal to the pituitary. (It appears that all doesn't always go right even with whole ferrets, given how about half of whole unbred females go on to develop marrow toxicity.)
Okay, so what about when the ferret has been neutered? Well, the adrenals (which also contain hormone generating tissue) can't tell the pituitary to quiet down and keep being stimulated by it.
Now, here is where this becomes a little bit me, a little bit you for several of us here:
The melatonin reduction (from too little darkness) plays a major role setting things in motion BUT THIS IS NOT A DIRECT CAUSE.
The pituitary plays a major role in the hormones it secretes BUT THERE IS NOT PITUITARY DISEASE.
Neutering plays a major role by preventing feedback BUT IT IS NOT JUST EARLY NEUTERING.
What is important is the *combination*, and there may be other factors which research will show to play roles as well.
-- Sukie (not a vet, and not speaking for any of the below in my private posts)
Recommended health resources to help ferrets and the people who love them:
Ferret Health List
http://www.smartgroups.com/groups/ferrethealth
FHL Archives
http://ferrethealth.org/archive/
AFIP Ferret Pathology
http://www.afip.org/ferrets/index.html
Miamiferrets
http://www.miamiferret.org/fhc/
International Ferret Congress Critical References
http://www.ferretcongress.org
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