Message Number: SG17224 | New FHL Archives Search
From: anaisdog@yahoo.com
Date: 2006-04-27 22:04:56 UTC
Subject: [ferrethealth] raven surgery results (long)
To: ferrethealth@smartgroups.com

thanks to the moderators for letting me post this.

I have a 5 yr MF female , Raven, who I had a melatonin chip put in on 3/4/06. she
had been chipped
once before, in June 05 with no ill effects at all at that time. on 3/5, I noticed her
looking lethargic, and by 3/6, all
that was coming out of her was smelly, green mucous slime. I took her to the vet
on 3/7 (it was the soonest I could get her
in), where they tested for all parasites and gave her sub q fluids. she's had chronic
diarrhea since 3/6. these are the
results of her surgery and I was hoping someone could lend an idea. My dr's
opinion is now that she has a food allergy.
currently, she is being free fed totally ferret and eukanuba feline and given 3 tsp
(about) per day of bob church's chicken
gravy recipe (more, if she'd eat it). the only that has changed in her diet is before
this happened, I let her eat science diet light / feline but I've
since removed it from her diet. Note, in the past two days, I tried giving her sd
feline z/d, since it is supposed to be
hypoallergenic, and the messy diarrhea, as opposed
to the just not well formed diarrhea is back. could she be allergic to all science diet
foods?


she's been on, in various combinations, the following medications:
pedipred
carafate
flagyl
amoixicilian
metrondiazole
baytril
viokase

During the surgery, he took out her left adrenal and did a biopsy on her intestines,
stomach, pancreas, lymph nodes and liver. These are the
results. she had, according to him, the angriest pancreas ever.

Her condition was chronic diarrhea, with lethargy. I've just started using the Viokase
and she seems to be on the upswing. she's on 1/4 of a 8mg
tablet, at least 3 times a day, given in chicken gravy. I really need some advice,
please.

Biopsy results

Souce/History - Chronic diarrhea
microscopic description - 1. Liver: the portal regions of the liver appear to be
within normal limits. Hepatocytes exhibit
minimal microvesicular-type degeneration. There i s miled intracellular biliary
pigment retention.
2. Intestine: There is a mild increase in intraepithelial
lymphocyctes. There are mild scattered accummulations
scattered accumulations of plasma cells and eosinophilis in the superficial lamina
propria. Mild edema and vascular congestion are present.
3. Adrenal Gland: there is scattered nodular hyperplasia within the
adrenal cortex.
4. Pancreas: There are no significant microscopic lesions.
5. Stomach: There are no significant microscopic lesions.
6. Lymph node: There is a mild scattered cystic degeneration. This
is incidental age-related finding in the ferret.

Diagnosis - 1. Liver degeneration, microvesticular-type, mild with attendant
cholestasis.
2. Adrenal Gland: Nodular hyperplasia, multicentric
3. Intestines: enteritis, lymphoplasmacytic and eosinophilic variant,
mild, widespread, chronic
4. Stomach: essentially, normal tissue
5. liver: cycstic degeneration, incidental

Comments - 1. Liver - the degenerative chagnes found in the liver are nonspecific
lesions, consistent with the response to the systemic metabolic
disturbances in this patient.
Correlation of these findings with the clinical history, physical findings,
and other diagonostic data will be important in
determining contributory factors for this patient.
No evidence of other specific predisposing factors or neoplasia was found
in the tissue sections examined/

2. Adrenal Gland: excision of the mass appears complete. Local
recurrence is not aticipated. There was no evidence of neoplasia in
the sections examined.
Adrenocortial hyperplasia, adrenocortical adenoma and
adrenocortical carcinoma are all relatively common lesions in the aged ferret
adrenal gland. these lesions are often associated with excessive
production of adrenocortical sex steriods. Clinically, these lesions
are associated with vulvar swelling the females, endocrine
dermathopathy and/or behavioral or reproductive abnormalities.
Recurrence of clinical signs in these patients may be due to the
development of asynchronous simimlar lesions in the contralateral adrenal
gland.

3. Intestines: the reactive and inflammatory changes noted are non-
specific, but the mild eosinophilic component can be seen in association with
underlying allergic/hypersensitivity disorders. Food allergies are the
primary differntial, however, endopoarasitism should be
ruled out through other ancillary diagnostic studies.

No evidence of other specific predisosing factors or neoplasia was found
in the tissue sections examined.

4. Pancreas: No evidence of specific predisposing factors, significant
inflammation or neoplasia was found in the tissue sections examined.

5. lymph node: cystic degeneration is an incidental age-related finding
in ferret in lymph nodes

no evidence of specific predisposing factors, significant inflammation or
neoplasia was found in the tissue sections examined.






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