From:
sukiec@optonline.net
Date: 2006-05-11 17:11:31 UTC
Subject: [ferrethealth] new Listeriosis treatment
To: ferrethealth@smartgroups.com
According to several sites on zoonotic diseases in several countries Lister=
iosis is a rare infection of the ferret.
Is the antibiotic below an okay one for ferrets?
This is a press release from Eureka! and those okay to carry here in full:
START PRESS RELEASE
Contact: Cherry Lewis
cherry.lewis@bristol.ac.uk
44-177-928-8086
University of Bristol =
New treatment for food poisoning
The antibiotic, fosfomycin, can treat Listeria in the body, despite it bein=
g ineffective in laboratory conditions
A team of researchers working at the University of Bristol has found a pote=
ntial new treatment for listeriosis, a deadly form of food poisoning. Their=
work is reported in Nature Medicine.
The group, led by Professor Jose Vazquez-Boland, has shown that one particu=
lar antibiotic =96 fosfomycin =96 can treat Listeria in the body, despite i=
t being ineffective in laboratory conditions.
Because it was not effective in the laboratory, this drug has never been co=
nsidered for the treatment of listeriosis, in spite of it reaching the infe=
ction sites more effectively than other antibiotics.
Professor Vazquez-Boland said: "Our results illustrate that antibiotic resi=
stance in the laboratory does not always mean that the drug will not work i=
n the infected patient. This work brings some optimism to the highly worryi=
ng problem of the increasing resistance to antibiotics."
The Listeria bacteria causes the food-borne disease, listeriosis. It often =
triggers a brain infection and kills up to 30% of those affected.
To test whether antibiotics are effective, bacteria are taken from patients=
and tested in the laboratory. These tests measure whether antibiotics can =
halt the growth of Listeria in laboratory conditions. Such tests are usuall=
y a measure of how effective the drug will be in the body.
When tested this way, Listeria had been shown to be resistant to the antibi=
otic, fosfomycin. As a consequence, this drug has never been considered for=
the treatment of listeriosis.
Dr Mariela Scortti, lead author on the paper, added: "Our findings warn abo=
ut the need to revise laboratory methods currently in use to determine the =
susceptibility or resistance of bacteria to such drugs, so that the tests r=
eflect better what actually happens in the body."
END PRESS RELEASE
=
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