Message Number: SG17339 | New FHL Archives Search
Date: 2006-05-12 02:09:45 UTC
Subject: [ferrethealth] abstracts of latest ferret medical studies

Vet Pathol. 2006 May;43(3):353-6.

Renal adenocarcinoma in a ferret.

Kawaguchi H, Miyoshi N, Souda M, Maeda H, Kawashima H, Gejima K, Uchida K, =
Umekita Y, Yoshida H.

8-35-1 Sakuragaoka, Kagoshima, 890-8544 (Japan). kawa@m3.kufm.kagoshima-u.a=

A spontaneous case of renal tumor was observed in a 7-year-old ovariectomiz=
ed female pet ferret (Mustela putorius furo). Clinical signs included exhau=
stion, emaciation, anorexia, and stooping position. At necropsy, a solid an=
d cystic mass replaced the left kidney and adrenal gland. The tumor was com=
posed of pleomorphic epithelial cells with a large number of giant cells. M=
etastases were recognized in the lung, liver, greater omentum, right renal =
pelvis, and systemic lymph nodes. Immunohistochemical stains revealed that =
the tumor cells were positive for CD10, cytokeratin (CAM 5.2), and Ki-67 (M=
IB-1). On the basis of morphologic and immunohistochemical features, the tu=
mor was diagnosed as a pleomorphic renal adenocarcinoma. This type of neopl=
asm is very rare in all species and has never been reported in a ferret.

and something different in a cousin, the BFF, which has been mentioned here=
at times because of how they differ for you zoo vets:

Vet Pathol. 2006 May;43(3):276-80.

Renal Tubular-cell Neoplasms in Black-footed Ferrets (Mustela nigripes)-38 =

Lair S, Barker IK, Mehren KG, Williams ES.

Departement de sciences cliniques, Faculte de medecine veterinaire, Univers=
ity of Montreal, C.P. 5000, St. Hyacinthe, Quebec J2S 7C6, (Canada). stepha=

Thirty-eight cases of renal tubular cell neoplasms were diagnosed in 184 ca=
ptive, adult (>1-year-old), black-footed ferrets (Mustela nigripes) examine=
d from 1985 to 1996. This prevalence (20.7%) is one of the highest reported=
for this neoplasm in a population of animals. These tumors rarely metastas=
ized (1/38), and usually were incidental postmortem findings, associated cl=
inical disease being present in only 3 (8%) of the 38 cases. The prevalence=
of renal tubular cell neoplasms found at postmortem examination increased =
linearly with age, up to 67% in ferrets >8 years old. Both males (prevalenc=
e =3D 19%) and females (prevalence =3D 24%) were affected. Multiple renal t=
umors were common, and seven ferrets (18.4% of affected animals) had bilate=
ral tumors. The cause of this neoplastic syndrome could not be determined. =
Since most of the animals affected by this condition were in their postrepr=
oductive years of life, the impact of this neoplastic syndrome on the capti=
ve propagation of this species is negligible.

Sent from website 5/11/06

-- Sukie (not a vet, and not speaking for any of the below in my private po=
Recommended health resources to help ferrets and the people who love them:
Ferret Health List
FHL Archives
AFIP Ferret Pathology
International Ferret Congress Critical References



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