From:
sukiec@optonline.net
Date: 2006-06-30 14:29:08 UTC
Subject: [ferrethealth] RE: Carafate/Sucralfate Protocol
To: ferrethealth@smartgroups.com
Thanks, Katherine. We've had longer recommendations from vets, especially =
in relation to meds, and my hubby had to use Carafate for a while after an =
esophageal procedure in which situation the gastroenterologist wanted 20 mi=
nutes minimum so in case that is based mostly on the behavior of Carafate i=
n general we've tended to go the longer time route just to be careful since=
no one seems to have really sure numbers for ferrets. That was many years=
ago, though. You are right, the experts' estimates on this timing for fer=
rets certain does vary and some are shorter than others.
The only printed study I can find which even relates doesn't provide data i=
n the bit I could find:
Gastroenterology. 1997 Dec;113(6 Suppl):S131-48.
What other regimens are under investigation to treat Helicobacter pylori in=
fection?
Unge P.
Department of Medicine, Lanssjukhuset Gavle Sandviken, Sweden.
I am trying to see if I can locate anything more recent on use timing. Thi=
s is interesting; normally (but not always) in things I have found Sucralfa=
te is not used with antacids because it likes an acidic environment but thi=
s is info on preventing ventilator use related pneumonia and both are used =
(though on separate schedules): <http://www.ahrq.gov/CLINIC/PTSAFETY/chap1=
7b.htm> . Not useful for us, but interesting given the combo.
In
http://www.mayoclinic.com/health/drug-information/DR202533
There is the following warning which could be useful for ferrets, too:
BEGIN QUOTE
Although certain medicines should not be used together at all, in other cas=
es two different medicines may be used together even if an interaction migh=
t occur. In these cases, your doctor may want to change the dose, or other =
precautions may be necessary. When you are taking sucralfate, it is especia=
lly important that your health care professional know if you are taking the=
following:
Ciprofloxacin or
Digoxin or
Norfloxacin or
Ofloxacin or
Phenytoin or
Theophylline=97Sucralfate may prevent these medicines from working properly=
END QUOTE
and later:
BEGIN QUOTE
Other medical problems
The presence of other medical problems may affect the use of sucralfate. Ma=
ke sure you tell your doctor if you have any other medical problems, especi=
ally:
Gastrointestinal tract obstruction disease=97Sucralfate may bind with other=
foods and drugs and cause obstruction of the gastrointestinal tract
Kidney failure=97Use may lead to a toxic increase of aluminum blood levels
END QUOTE
and it looks like in humans the current timing recommendations are LONGER f=
or humans than they were about a dozen years ago or so when Steve had it:
BEGIN QUOTE
Sucralfate is best taken with water on an empty stomach 1 hour before meals=
and at bedtime, unless otherwise directed by your doctor.
END QUOTE
Author wrote:
> Here are three posts where Dr. Williams recommends giving carafate 10 min=
utes prior to feeding. I normally do 10-15 minutes.
> http://ferrethealth.org/archive/browse.php?msg=3DSG3096
> http://ferrethealth.org/archive/browse.php?msg=3DYG2625
> http://ferrethealth.org/archive/browse.php?msg=3DYG6046
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