Message Number: SG17989 | New FHL Archives Search
From: sukiec@optonline.net
Date: 2006-07-25 20:19:37 UTC
Subject: [ferrethealth] RE: neural crest development timing and domestication
To: ferrethealth@smartgroups.com

Sorry. That is actually about 4 or 5 short quoted segments and in different=
order than in the article to make the summary most readable.

For some reason on sending the lines between segments wound up lost. =


It is not one long quote.

Author wrote:
> A must-read article in the NY Times. Hopefully, people can get it if =

> they go there fast enough. If not, there are always off-shoot =

> reports elsewhere when the Times carries an interesting topic (which =

> this is), and libraries often carry the articles.
> http://www.nytimes.com/2006/07/25/health/25rats.html? =

> _r=3D1&th&emc=3Dth&oref=3Dslogin
> This links into the old "star gene" hypothesis.
> Given the medical problems that are also associated with some neural =

> crest genetic variants it would be interesting if domestication =

> itself might help set the stage for certain vulnerabilities.
> Title and author in case a library is needed:
> Nice Rats, Nasty Rats: Maybe It=92s All in the Genes
> by Nicholas Wade
> QUOTING SEGMENTS
> > Could a single gene that affects the timing of neural crest cell =

> > development underlie the whole phenomenon of animal and human =

> > domestication?
> > One possibility is that a handful of genes =97 perhaps even just one =

> > =97 underlie all the changes seen in domestication. A structure in =

> > the embryo of all vertebrates, known as the neural crest, is the =

> > source of cells that constitute much of the face, skull and pigment =

> > cells, and many parts of the peripheral nervous system and =

> > endocrine system. If the genes in the neural crest cells were =

> > delayed just a little in coming into action, a whole range of =

> > tissues could be affected, including the maturation of the adrenal =

> > glands that underlies the first fear response of young animals, Dr. =

> > Fitch has written.
> > His strategy is to cross the tame rats with the ferocious rats and =

> > then score the progeny for how much of each trait they inherit. He =

> > hopes to identify 200 sites along the genome at which the tame and =

> > ferocious rats differ. If one or more of the sites correlate with =

> > tameness or fierceness in the progeny, they will probably lie near =

> > important genes that underlie one of the two traits.
> >
> > The genes, if Mr. Albert finds them, would be of great interest =

> > because they are presumably the same in all species of domesticated =

> > mammal. That may even include humans. Richard Wrangham, a =

> > primatologist at Harvard, has proposed that people are a =

> > domesticated form of ape, the domestication having been self- =

> > administered as human societies penalized or ostracized individuals =

> > who were too aggressive.
> -- Sukie (not a vet, and not speaking for any of the below in my =

> private posts)
> Recommended health resources to help ferrets and the people who love =

> them:
> Ferret Health List
> http://www.smartgroups.com/groups/ferrethealth
> FHL Archives
> http://ferrethealth.org/archive/
> AFIP Ferret Pathology
> http://www.afip.org/ferrets/index.html
> Miamiferrets
> http://www.miamiferret.org/fhc/
> International Ferret Congress Critical References
> http://www.ferretcongress.org

=

=




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