From:
sukiec@optonline.net
Date: 2006-09-11 19:19:22 UTC
Subject: [ferrethealth] RE: mixing medicine weight needed
To: ferrethealth@smartgroups.com
Mary Jo, the important thing to know is HOW MANY MG PER DOSE IS YOUR VET HAVING GIVEN?
Then people can help you figure out what you need.
Even if your vet is out this will be in the chart and another vet there or a tech will be able to help.
Remember, what matter is the CONCENTRATION: the mg amount per ml. If people help you made 15 ml there is going to be TWICE AS MUCH MEDICATION in that 15 ml as there would be in 30 ml.
This is why the rules remind people not to give just the ml amount (the volume/amount of liquid given) but to also include the mg/ml for meds that don't have just one standard concentration.
Think of it like chicken soups. You can make one with a high concentration of chicken which is like a thick puree, but you can also make a thin broth which has a low concentration of chicken. If the individual needed a lot of chick then the broth just would not work. On the other hand, the same amount of concentrated chicken puree might be too much chicken for one who needed a smaller dose.
Here is some info I provided in the past:
I was asked off list to provide these pieces of information to help list members:
Here is some information for several concentrations found for Prednisolone in recent years, if memory serves (some for Pediapred and some for generics, and there are even more when the med is compounded because then the possible range is larger).
1mg/ml
2/mg/ml
5mg/ml
7mg/ml
As you see, the last has 7 times more medicine than the first in the same volume.
The third has 5 times as much medication as the first in the same volume.
The second has 2 times as much medication as the first in the same volume.
One of the people interested in the dosing conversation is giving the 2mg/ml concentration. Here is how some common amounts quoted work out in relation to that concentration.
0.20 ml x 2 mg/ml means that each dose gives 0.4 mg of med at that concentration
0.25 ml x 2 mg/ml means that each dose gives 0.5 mg of the med (half an mg)
0.5 ml x 2 mg/ml means that each dose give 1 milligram of the med
So, a ferret who is getting 0.25 ml of the 2 mg/ml prednisolone 2 time a day will be getting one milligram of prednisolone each day.
If the ferret were on the 1 mg/ml concentration the ferret would be getting only half that much medication even though the ml levels would be the same because there is only half as much med in mg per ml.
You can see how the amounts of actual medication received go up a lot more for the same volume if the medication is more concentrated in the fluid (a higher mg level for each ml).
---
Weight also matters for dosing many meds, which is why the vet texts tell how much in milligrams to give for each kilogram of weight.
Author wrote:
> Seems I have smeared the writing on my bottle of Trimox (125mg per 5ml). It is a big bottle (150mg) so we just mix what we need. I think my writing says 22 grams powder (the Trimox) to 23 ml water to make 30ml. I just really can't make it out.
> On the bottle printed it says to mix the entire bottle you mix 88ml of water that provides 150 ml of suspension. Can someone help me out here and tell me the proper mixture to make either 15ml or 30ml. I called my vet but he is out until Wednesday and the vet that is substituting for him doesn't treat ferrets. thanks, MJB
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