Message Number: SG18505 | New FHL Archives Search
From: Tonytclarke@aol.com
Date: 2006-10-21 23:48:22 UTC
Subject: [ferrethealth] RE: possible campylobacter
To: ferrethealth@smartgroups.com

I have found this (helicobacter M) very difficult to get to grips with the treatment regimes. After reading dozens of articles on the treatment it seems to me that the regimes (the initially used 3 part and later 2 part) are based on treatment successful against H pylori (in humans), however I have unearthed the following (only an extract)

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Therapy.

Limited studies of antibiotic therapy for H. mustelae indicate that it is sensitive in vitro to many of the agents effective against H. pylori. The MIC of amoxicillin is 1 to 2 log units higher than for H. pylori 4, 221, 313, and therefore combination treatment containing amoxicillin may be less effective in ferrets than in humans 4, 313. The combination of ranitidine bismuth citrate and clarithromycin is effective therapy for H. mustelae infection in ferrets 263. Both these drugs are often used to treat H. pylori infection in humans, although this combination is not a generally recommended treatment regimen.

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http://cmr.asm.org/cgi/content/full/14/1/59?view=full&pmid=11148003

H. pylori in humans is normally only treated when patients present with ulcers so an antacid is used to calm the ulcer, not treat the helicobacter.
As my Suki does not show signs of ulcers then the antacid (ranitidine bismuth citrate) can be omitted (I think this was my vets thinking).

Tony. (also not a vet)
My home is ferret proof - my heart is not.







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