Message Number: FHL2118 | New FHL Archives SearchFrom: Sukie Crandall
Date: Mon, 06 Aug 2007 15:14:23 -0400
To: ferrethealth@yahoogroups.com, Jennifer Bell <menchador@gmail.com>
Subject: [ferrethealth] Re: Migrating Parasites
That's all new to me.
Are the parasites in the red blood cells, the macrophages, or elsewhere?
Pages 1-5 of this resource from Dr. Williams may help since it comes=20
up in page 4
http://www.afip.org/vetpath/WSC/wsc04/04wsc08.pdf
http://www.nal.usda.gov/awic/pubs/oldbib/ferretla.htm
> 466
> "Actinomycosis and torulosis in the ferret (Mustela furo L)." G.=20
> Skulski and W.S.C. Symmers. Journal of Comparative Pathology=20
> 64:306-311(1954).
> NAL call number: 41.8 J82
> KEYWORDS: mycotic diseases; Cryptococcus; Encephalitozoon
> cuniculi; Histoplasma farcinimosum.
http://netvet.wustl.edu/species/ferrets/ferretla.txt
(same reference)
These might be helpful or useless depending on what turns up
Encephalitozoon (a microsporidian) in human macrophages
http://iai.asm.org/cgi/content/full/75/4/1619?view=3Dlong&pmid=3D17178789
general on that genus which I gather has some problematic species for=20
rabbits:
http://www.ebi.ac.uk/2can/genomes/eukaryotes/
Encephalitozoon_cuniculi.html
> ... Microsporidians are primordial eukaryotes lacking=20
> mitochondriae, they are intracellular parasites of other
> eukaryotes, ranging from protozoans to humans. To date, more than=20
> 1,200 species belonging to 143 genera have been described as=20
> parasites infecting a wide range of vertebrate and invertebrate=20
> hosts. Microsporidia, are characterised by the production of=20
> resistant spores that vary in size, depending on the species. They=20
> possess a unique organelle, the polar tubule or polar filament ,=20
> which is coiled inside the spore.
...
> Microsporidia are being increasingly recognised as opportunistic=20
> infectious agents worldwide. Cases of microsporidiosis have been=20
> reported in developed as well as in developing countries.
...
> Infection with E. cuniculi transiently increases NK (natural=20
> killer) cell activity, causes hepatosplenomegaly with ascites,=20
> alters brain and kidney architecture, alters host responses to=20
> transplanted tumors, and reduces cellular and humoral responses to=20
> a variety of immunogens... Natural infection of laboratory mice and=20
> rats would compromise studies involving the gastrointestinal,=20
> renal, and central nervous system and possibly others.
>
> This organism has a very compact genome (the smallest eukaryotic=20
> genome known to date) of 2.9 Mbases. The genome is organised into=20
> 11 chromosomes.
>
> E. cuniculi should be included in the expanding spectrum of=20
> potentially life-threatening opportunistic pathogens that infect=20
> the brain. Detection of the parasite in cerebrospinal fluid may be=20
> difficult, since the number of spores may be low. Microscopical=20
> examination of urinary sediment, however, appears to be a simple=20
> method for the diagnosis of disseminated encephalitozoonosis
>
http://www.cns.fr/externe/English/Projets/Projet_AD/AD.html
> This organism has a very compact genome (the smallest eukaryotic=20
> genome known to date) of 2.9 Mbases. The genome is organized into=20
> 11 chromosomes. Sequencing of the complete genome is underway using=20
> a shotgun approach on a plasmidic library as well as BAC end=20
> sequencing. The results may lead to new treatments for=20
> microsporidial infections, as well as insights into the positioning=20
> of the microsporidae in the eukaryotic classification scheme.=20
> Sequencing of the Encephalitozoon cuniculi genome is a=20
> collaborative project between Genoscope and the team led by Pr.=20
> Christian Vivares (Laboratoire de Protistologie Mol=E9culaire et=20
> Cellulaire des Parasites Opportunistes, Universit=E9 Blaise Pascal,=20
> Aubi=E8re, France)
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
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