Message Number: FHL2930 | New FHL Archives Search
From: "Sukie Crandall"
Date: 2007-11-04 16:50:09 UTC
Subject: [ferrethealth] Re: Question about Lymphoma

Reactive tends to mean
"Beginning again"
"in response to"

There are also causes of enlarged nodes which are reactive
(as in response to serious infection) which are NOT lymphoma
or lymphosarcoma. You may be referring to that. In that case
you'd be referring to lymphadenopathies (reactive, lymphoma,
and metastases).

Also there is a form of lymphoma, the immunoblastic-polymorphous
variant which looks to be caused by some type of viral exposure 2 or
3 years before the lymphoma arises. This is the form called
"clumping lymphoma" in the ferret community vernacular because
there tend to be multiple individuals who were in the home at the
time of exposure who die. We have twice been through that in our
home in our quarter century plus with ferrets, making it the single
most common cause of death in our ferret family.

You can read about it and about the work on it done at MIT (Study
ended when funding could not continue long enough.) by going to
page 2 of
which I highly recommend reading
in 1995, researchers at the
Massachusetts Institute of Technology were able
to transmit lymphoma between ferrets with cell-
free extracts, suggesting a possible viral cause
for lymphoma, or at least some forms of it. The
development of lymphoma in this experiment
took several years in inoculated individuals, and
not all inoculated ferrets developed lymphoma,
but the results of this study are too intriguing to
ignore. To date, however, a virus has yet to be
identified or isolated from malignant lymphoma
in ferrets.

Not a vet, but I think I got that right...

--- In, "DebraJean" <debifuzzyloving@...> wrote:
> I have a question and would like to direct this to Dr. Williams if
> possible.
> What causes REACTIVE Lymphoma?
> I have lost 2 ferrets to this and the lab results indicate that it
> wasn't caused due to cancer of any type. All the tissue and fluid
> biopsies came back negitive. BTW, I lost both boys.
> Debi

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