Message Number: FHL3056 | New FHL Archives Search
From: "dalemarchand"
Date: 2007-11-16 15:14:11 UTC
Subject: [ferrethealth] Re: Depo-Medrol for treating insulinoma?

We used Depo-Medrol injections to treat insulinoma in one ferret for
nearly 2 years successfully. Our ferret (Moon) was non-responsive to
prednisone and prednisolone in even the highest doses, and our vet at
the time offered that Depo-Medrol had been used successfully in cats,
I believe. Interestingly, she too had been adrenal, and had
successful surgery to remove her left adrenal gland, but had pulled
through that operation a couple of years before the insulinoma

In any event, we started with a "middle-of-the-road" dosage (I've no
idea what it was too long ago) and proceeded to gradually
reduce both the dosage and the frequency of injections from every 2
weeks to every 5-6 weeks. We got very good at detecting when it was
about time for another shot.

Our vet told us to expect a maximum of 6 months. Moon survived
another 2 years on the injections. She definitely developed the "pred
belly" and her hair thinned considerably over time, but was actually
fairly active and very comfortable until the very end.

We also tried Depo-Medrol injections on a ferret who'd had insulinoma
surgery (nodules removed) and still had low glucose levels.
Prednisone and prednisolone both didn't work in him either, but
unfortunately neither did Depo-Medrol. He passed away a short 3
months after his surgery.

So, I can certainly vouch that in one situation it worked well, but it
is certainly not a certainty.

Dale Marchand

--- In, "Karen McCabe" <yahoo@...> wrote:
> On November 5 I brought home a little guy from my vets office. He is
> estimated at 6 years old, adrenal and insulinomic. My vet has him on
> Depo-Medrol, rather then daily pred, for the insulinoma. So far his
> glucose has been ranging from 64 to 116, with most readings in the
> 90's. I'm trying to find info on using Depo-Medrol in ferrets with
> insulinoma but I'm not having much luck. Is anyone here aware of where
> I might info on this? Has anyone else ever used Depo-Medrol in this
> manner?
> Any info would be appreciated!
> Karen McCabe

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