From:
"Sukie Crandall"
Date: 2007-11-19 02:44:13 UTC
Subject: [ferrethealth] Re: current ECE protocol?
To: ferrethealth@yahoogroups.com
> In an older ferret ECE is an extremely serious, often dehydrating
> coronavirus which can last for months and can wind up with
> secondary infections involved. It can be fatal in an already
> compromised ferret. (So can some other causes of GI illness
> such as E. coli infection, one of the nastier and less looked for
> genera of coccidia, etc.)
>
I've been asked for some more info on each of these, E. coli, and
coccidia.
These are good places to start:
Coccidia:
http://ferrethealth.org/archive/YPG590
http://ferrethealth.org/archive/YPG550
http://ferrethealth.org/archive/SG17961
E. coli:
http://ferrethealth.org/archive/FHL2147
http://www.pubmedcentral.nih.gov/articlerender.fcgi?
tool=pubmed&pubmedid=15583337
http://www.jwildlifedis.org/cgi/reprint/37/3/617
and from PubMed an assortment of things like:
BEGIN QUOTE
J Infect Dis. 2002 Feb 15;185(4):550-4. Epub 2002 Jan 22. Links
Ferrets as a model system for renal disease secondary to intestinal infection with
Escherichia coli O157:H7 and other Shiga toxin-producing E. coli.
Woods JB, Schmitt CK, Darnell SC, Meysick KC, O'Brien AD.
Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda,
Maryland 20814-4799, USA.
Ferrets were evaluated as a possible small animal model for the development of colitis
and/or signs of the hemolytic uremic syndrome after oral infection with Escherichia coli
O157:H7 or other Shiga toxin--producing E. coli (STEC). Ferrets treated with streptomycin
(Stm) had higher counts of E. coli O157:H7 strain 86-24 Stm-resistant (Stm(r)) or O91:H21
strain B2F1 Stm(r) in their stools than non--Stm-treated animals. None of the animals
displayed evidence of colitis, but Stm-treated animals fed strain 86-24 Stm(r) exhibited
weight loss significantly greater than that exhibited by ferrets fed an isogenic mutant
negative for the adhesin intimin. Moreover, 11 (23%) of the 47 Stm-treated ferrets
inoculated with 86-24 Stm(r) or B2F1 Stm(r) developed hematuria and/or histological
damage to glomeruli or thrombocytopenia, compared with 0 of 14 uninfected control
animals receiving Stm in water. Thus, the ferret may serve as a model for renal disease
secondary to intestinal infection with STEC.
PMID: 11865409 [PubMed - indexed for MEDLINE]
END QUOTE
etc.
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