From:
Sukie Crandall
Date: 2007-11-22 16:11:45 UTC
Subject: [ferrethealth] composition of cerebrospinal fluid in ferrets
To: ferrethealth@yahoogroups.com
In case needed for anyone's testing, here is the abstract to help=20
locate the article (w link to article for member vets):
http://avmajournals.avma.org/doi/abs/10.2460/ajvr.2004.65.758
BEGIN QUOTE OF ABSTRACT
Abstract
American Journal of Veterinary Research
June 2004, Vol. 65, No. 6, Pages 758-760
doi: 10.2460/ajvr.2004.65.758
Composition of cerebrospinal fluid in clinically normal adult ferrets
Simon R. Platt , BVM&S Patricia M. Dennis , DVM, MSL Leo J. McSherry ,=20
DVM Cheryl L. Chrisman , DVM, MS R. Avery Bennett , DVM, MS
Department of Small Animal Clinical Sciences, College of Veterinary=20
Medicine, University of Florida, Gainesville, FL 32610. (Platt,=20
Dennis, McSherry, Chrisman, Bennett); Present address is Centre for=20
Small Animal Studies, Animal Health Trust, Newmarket, Suffolk, England=20
CB8 7UU. (Platt); Present address is Department of Veterinary=20
Preventive Medicine, College of Veterinary Medicine, The Ohio State=20
University, Columbus, OH 43202. (Dennis); Present address is IDEXX=20
Laboratories, 1370 Reynolds Ave, Ste 109, Irvine, CA 92614.=20
(McSherry); Present address is Department of Small Animal Clinical=20
Studies, School of Veterinary Medicine, Univesity of Pennsylvania,=20
Philadelphia, PA 19104. (Bennett)
Objective=97To determine the protein and cellular composition of CSF in =
healthy adult ferrets.
Animals=9742 clinically normal adult ferrets.
Procedure=97CSF samples were collected from the cerebellomedullary=20
cistern of anesthetized ferrets by use of disposable 25-gauge, 1.6-cm-
long hypodermic needles. Samples were processed within 20 minutes=20
after collection. The number of WBCs and RBCs per microliter of CSF=20
was counted by use of a hemacytometer. The total protein concentration=20
was determined by use of an automated chemistry analyzer.
Results=97Total WBC counts (range, 0 to 8 cells/=B5L; mean, 1.59 cells/=B5L=
)=20
in CSF of ferrets were similar to reference range values obtained for=20
CSF from other species. Twenty-seven CSF samples had < 100 RBCs/=B5L=20
(mean, 20.3 RBCs/=B5L). A small but significant effect of blood=20
contamination on WBC counts was found between the 27 CSF samples with=20
< 100 RBCs/=B5L and the remaining samples. Protein concentrations in CSF =
of ferrets (range, 28.0 to 68.0 mg/dL; mean, 31.4 mg/dL) were higher=20
than has been reported for the CSF of dogs and cats. A significant=20
effect of blood contamination on the CSF protein concentration was not=20
found.
Conclusions and Clinical Relevance=97 We have established reference=20
range values for WBC counts and protein concentrations in CSF from=20
healthy adult ferrets that may be useful in the clinical investigation=20
of CNS disease. Results of our study indicate that the WBC count is=20
significantly affected by blood contamination of the CSF sample. (Am J=20
Vet Res 2004;65:758=96760)
END QUOTE OF ABSTRACT
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
[Non-text portions of this message have been removed]
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