From:
Sukie Crandall
Date: 2007-12-08 06:34:17 UTC
Subject: [ferrethealth] some new abstracts
To: ferrethealth@yahoogroups.com
BEGIN QUOTED ABSTRACTS OR STUDY NAMES WHEN NO ABSTRACT
Parasitol Res. 2007 Aug;101 Suppl 1:57-62.
Imidacloprid plus Moxidectin to Prevent Heartworm Infection=20
(Dirofilaria immitis) in Ferrets.
Schaper R, Heine J, Arther RG, Charles SD, McCall J.
Bayer HealthCare AG, Animal Health, Leverkusen, Germany
Ferrets are susceptible to Dirofilaria immitis infection and develop a=20
disease comparable to that in cats and dogs. Treatment options are=20
limited, thus prevention would be a viable alternative. A study was=20
conducted to evaluate the efficacy of a combination of 10% w/v=20
imidacloprid plus 1.0% w/v moxidecin spot-on to prevent patent D.=20
immitis infection in experimentally infected ferrets when administered=20
once 30 days post-infection. Twelve ferrets were acclimated to the=20
study facility for seven days. The ferrets were free of heartworm=20
infection prior to the artificial infection, as demonstrated by=20
negative test results onmicrofilarial and antigen tests. On study day=20
-30, the twelve ferrets were artificially infected with 25 infective,=20
thirdstage larvae of D. immitis. On study day -1, the twelve ferrets=20
were randomised and allocated to two study groups so that each group=20
contained six ferrets. On study day 0, the animals assigned to group 1=20
were treated with a combination of 10% imidacloprid / 1% moxidectin at=20
a dose of 0.4 ml per ferret. The animals assigned to group 2 served as=20
untreated controls. On study day 124, the ferrets in both study groups=20
were euthanised and necropsied to determine the worm burden. Ferrets=20
in the control group (group 2) were adequately infected with D.=20
immitis at necropsy to allow assessment of the treatment group in this=20
study (GM =3D 17.2worms). The efficacy of a combination of 10%=20
imidacloprid / 1.0% moxidecin against artificial infections with D.=20
immitis in ferrets was 100% when administered once, at a target dosage=20
of 0.4 ml, 30 days post-infection. No adverse events were observed=20
which were considered to be treatment related.
PMID: 17661108 [PubMed - in process]
Vet Rec. 2007 Dec 1;161(22):759-60.
Segmental atresia of the uterus associated with hydrometra in a ferret.
Batista-Arteaga M, Alamo D, Herr=E1ez P, Santana M, Rodr=EDguez F, Ni=F1o T=
,=20
Gracia A.
Unit of Reproduction and Obstetrics, Las Palmas Veterinary College,=20
University of Las Palmas de Gran Canaria, Trasmonta=F1a 35416 Arucas,=20
Las Palmas, Spain.
PMID: 18056015 [PubMed - in process]
END QUOTES
There is also one on cortical disruption that probably won't be of=20
interest to most but those who want it can look in Exp Neurol. 2007=20
Oct 23 for cortical dysplasia.
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
[Non-text portions of this message have been removed]
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