From:
Sukie Crandall
Date: 2007-04-16 01:10:08 UTC
Subject: [ferrethealth] some veterinary studies 2002 into 2006 located
To: ferrethealth@yahoogroups.com, ferret-l@LISTSERV.FERRETMAILINGLIST.ORG
See:
http://nal.usda.gov/awic/pubs/Ferrets06/feed_nutrit_metab.htm
for a number of ferret nutritional studies.
Now, for some veterinary ones:
on diabetes:
<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3D1255590>
The FULL article is present at this location.
BEGIN QUOTE
Can Vet J. 2005 October; 46(10): 895=96897.
Copyright This is an Open Access article: verbatim copying and
redistribution of this article are permitted in all media for any=20
purpose,
provided this notice is preserved along with the article's original URL.
Histopathologic lesions of diabetes mellitus in a domestic ferret
Marie-Odile Benoit-Biancamano,
Michel Morin, and Isabelle Langlois
D=E9partement de Pathologie et Microbiologie (Benoit- Biancamano,
Morin); Clinique de M=E9decine Zoologique, Centre Hospitalier
Universitaire V=E9t=E9rinaire (Langlois), Facult=E9 de M=E9decine V=E9t=E9r=
inaire,
Universit=E9 de Montr=E9al, 3200, rue Sicotte, St-Hyacinthe, Qu=E9bec J2S 2=
M2.
A 2-year-old ferret was referred with a diagnosis of diabetes mellitus.
The animal died despite insulin therapy and was submitted for necropsy.
Light microscopic examination revealed a mild hepatic lipidosis and
pancreatic lesions consisting of a diffuse vacuolation of the=20
Langerhans=92
islet cells with a periodic acid-Schiff positive material compatible=20
with
glycogen.
END QUOTE
Being unable to produce images here I can not provide that entire=20
article
above for you in the messages, but you can get it at the URL given=20
and the
pdf is here:
http://www.pubmedcentral.nih.gov/picrender.fcgi?
artid=3D1255590&blobtype=3Dpdf
You will LOVE this; it is a 25 page, highly comprehensive list of=20
ferret medical
studies from 2002 into 2006:
http://nal.usda.gov/awic/pubs/Ferrets06/veterinary.htm
I'd love to get this article by Tom Willard whose doctorate is in=20
veterinary
nutrition. If his name rings a bell he has Performance Foods which=20
makes
Totally Ferret:
BEGIN QUOTE
> Willard, T.R. (2002). Ferrets. Exotic DVM 4(4): 36-37. ISSN:=20
> 1521-1363.
>
> NAL Call Number: SF981 .E96
>
> Descriptors: ferrets, anatomy, physiology, diets, feed formulation,=20
> nutrient requirements.
END QUOTE
Given Hilbert's repeated bouts with allergic dermatitis, sometimes with
complications, I'd enjoy gathering this, too:
BEGIN QUOTE
White, S.D. (2006). Rabbit, rodent and ferret dermatology. In: Ahead of
the curve: OVMA Conference Proceedings., January 26, 2006-January
28, 2006, Ontario Veterinary Medical Association: Milton, Canada, p.=20
102-
115.
Online: http://www.ovma.org
Descriptors: ferrets, rabbits, rodents, dermatology, etiology, alopecia,
clinical aspects, diagnosis, drug therapy, ectoparasites, pruritus, skin
diseases.
END QUOTE
Intriguing:
BEGIN QUOTE
Schoemaker, N.J., J. Wolfswinkel, J.A. Mol, G. Voorhout, M.J.L. Kik,
J.T. Lumeij, and A. Rijnberk (2004). Urinary glucocorticoid excretion in
the diagnosis of hyperadrenocorticism in ferrets. Domestic Animal
Endocrinology 27(1): 13-24. ISSN: 0739-7240.
NAL Call Number: QL868.D6
Abstract: Hyperadrenocorticism in ferrets is usually associated with
unaltered plasma concentrations of cortisol and adrenocorticotropic
hormone (ACTH), although the urinary corticoid/creatinine ratio (UCCR)
is commonly elevated. In this study the urinary glucocorticoid excretion
was investigated in healthy ferrets and in ferrets with
hyperadrenocorticism under different circumstances. In healthy ferrets
and in one ferret with hyperadrenocorticism, approximately 10% of
plasma cortisol and its metabolites was excreted in the urine. High-
performance liquid chromatography (HPLC) revealed one third of the
urinary corticoids to be unconjugated cortisol; the other peaks mainly
represented cortisol conjugates and metabolites. In 21 healthy sexually
intact ferrets, the UCCR started to increase by the end of March and
declined to initial values halfway the breeding season (June). In=20
healthy
neutered ferrets there was no significant seasonal influence on the=20
UCCR.
In two neutered ferrets with hyperadrenocorticism the UCCR was=20
increased,
primarily during the breeding season. In 27 of 31 privately owned=20
ferrets
with hyperadrenocorticism, the UCCR was higher than the upper limit=20
of the
reference range (2.1 x 10(-6)). In 12 of 14 healthy neutered ferrets
dexamethasone administration decreased the UCCR by more than 50%,
whereas in only 1 of the 28 hyperadrenocorticoid ferrets did the UCCR
decrease by more than 50%. We conclude that the UCCR in ferrets=20
primarily
reflects cortisol excretion. In healthy sexually intact ferrets and=20
in ferrets with
hyperadrenocorticism the UCCR increases during the breeding season. The
increased UCCR in hyperadrenocorticoid ferrets is resistant to=20
suppression
by dexamethasone, indicating ACTH-independent cortisol production.
Descriptors: ferrets, hyperadrenocorticism, disease diagnosis, urine,
glucocorticoids, cortisol, excretion, metabolites, creatinine,=20
breeding season,
seasonal variation, dexamethasone, urinary corticoid-creatine ratio=20
(UCCR).
END QUOTE
Well, I could quote on and on, but I think many will want to make a=20
copy of the
list at that URL and retain it.
Sukie (not a vet)
Current FHL address:
http://groups.yahoo.com/group/ferrethealth
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
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