From:
"Sukie Crandall"
Date: 2007-04-17 22:26:24 UTC
Subject: [ferrethealth] Re: Anyone familiar with corynebacterium?
To: ferrethealth@yahoogroups.com
You sent me to the refs but I have NOT been particularly successful.
There are multiple types of corynebacteria.
>From a human source:
http://www.emedicine.com/med/topic459.htm
It is encountered in dental disease in ferrets:
http://www.afip.org/ferrets/dental/dentaldz.htm
and
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&list_uids=7478754&dopt=Abstract
and possibly normal in small amount for their eyes
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1463-5224.2006.00475.x?
journalCode=vop
So far this is all I've found on treatment in any location in a ferret:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8891937&query_hl=2&itool=p
ubmed_docsum
BEGIN QUOTE
J Clin Periodontol. 1996 Sep;23(9):853-60.
Links
The effect of cyclosporin-A on the oral microflora at gingival sulcus of the ferret.
Fischer RG, Edwardsson S, Klinge B, Attstrom R.
Department of Periodontology, Lund University, Malmo, Sweden.
The effect of cyclosporin-A (CyA) on the dentogingival flora of
ferrets with healthy and experimentally induced periodontal
breakdown was studied. Five animals were given 10 mg/kg/d
CyA. At the start of the experiments (day 0), ligatures were
placed around 4 teeth in the right upper and lower jaws;
corresponding contralateral teeth on the left side served as
control. On days 0 and 28 (end of the experiment),
microbiological samples were collected from the gingival sulcus
of the experimental and the control teeth and from closely
located gingival mucosa membrane. The samples were subjected
to viable counts and to darkfield microscopic analyses. On day 0,
facultative anaerobic rods, mainly Pasteurella spp, Alcaligenes spp,
Corynebacterium spp. and Rothia spp dominated in the viable counts.
No anaerobic bacteria were detected in the viable counts. On day 28
spirochetes increased in the experimental gingival sulcus samples
and anaerobic bacteria appeared in most of the samples and
constituted 40-60% of the total cultivable flora; Fusobacterium
necrophorum and Eubacterium spp. predominated in the samples
from the experimental sites. The results of the present study were
compared with those of our previous investigation of ferrets not
medicated with cyclosporin but also subject to experimental ligature
periodontitis. Eubacterium spp. were absent in the animals not treated
with cyclosporin, while this species was frequently present in the
immunosuppressed ferrets. The results indicate that the presence of
the large numbers of gram negative rods and of anaerobic bacteria may
have enhanced the inflammatory process and further provoked the
gingival overgrowth observed.
PMID: 8891937 [PubMed - indexed for MEDLINE]
END QUOTE
Related animal but no abstract:
Vet Rec. 2002 Apr 20;150(16):524.
Links
Comment on:
Vet Rec. 2002 Mar 16;150(11):355.
Corynebacterium ulcerans in free-ranging otters.
Foster G, Patterson T, Howie F, Simpson V, Davison N, Efstratiou A, Lai S.
PMID: 12017529 [PubMed - indexed for MEDLINE]
Is this by any chance an ADV positive ferret? See:
http://www.wessexferretclub.co.uk/aleutian%20d..htm
another (uterine):
http://www.ferret.org/newsletter/2000/pyometra.pdf
Sukie (not a vet)
Current FHL address:
http://groups.yahoo.com/group/ferrethealth
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
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