From:
"Sukie Crandall"
Date: 2007-02-12 00:18:09 UTC
Subject: [ferrethealth] Re: Comatose Ferret
To: ferrethealth@yahoogroups.com
DMG stimulates insulin release, as I recall. That
would make it exactly the wrong thing for insulinoma
but possibly good for diabetes -- the same precautions
as should be taken for supplemental chromium.
http://147.52.72.117/IJMM/2001/volume8/number5/531-532.pdf
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 8: 531-532, 2001
531
Potentiation by glutamic acid dimethyl ester of GLP-1
insulinotropic action in fed anaesthetized rats
JESUS CANCELAS1, MARIA L. VILLANUEVA-PE=D1ACARRILLO1,
ISABEL VALVERDE1 and WILLY J. MALAISSE2
1
Fundaci=F3n Jim=E9nez Diaz, Madrid, Spain; 2Laboratory of Experimental Med=
icine,
Brussels Free University, Brussels, Belgium
Received June 25, 2001; Accepted July 26, 2001
Abstract.
The dimethyl ester of L-glutamic acid (DMG)
stimulates insulin release and was proposed as a possible
insulinotropic tool in the treatment of non-insulin-dependent
diabetes...
As to comas:
Ferrets don't get true strokes but they do at times throw
thomboses (clots). We had one with kidney disease who
threw a clot and was fully comatose for about three days.=20
Each night we would take Spot to the Emergency vet where
he would be monitored all night and each morning we would
take him back to our vets where he would be monitored all day.
About dawn one day at the Emergency hospital he came
around. After a few months the only trace of his experience
was a bit of residual sensory and motor damage in one foot
which he learned to manage okay. He never threw another clot
and lived longer than expected with his level of kidney damage
(which was secondary to getting ECE at an older age).
In the case of your ferret I wonder if the brain simply became
too sugar deprived rather than there being anything like a
thrombosis. That would fit better.
I would really look a lot more into DMG before ever giving that
again, I think.
Sukie (not a vet)
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