From:
AFERRETVET@cs.com
Date: 2007-03-08 18:52:49 UTC
Subject: [ferrethealth] Re:Pimobendan
To: ferrethealth@yahoogroups.com
Hello Don,
There are 2 medications that can be used to
help strengthen the contraction of the heart muscles.
Digoxin and Pimobendan are the 2 choices. Both of these
drugs should be used along with other cardiac drugs such
as an ACE inhibitors and furosemide (Lasix).
Digoxin has some safety concerns. Digoxin toxicity is
a real problem that can cause real side effects. Monitoring
of blood levels of digoxin is often recommended to avoid
toxicity problems.
Pimobendan on the other hand is much safer than digoxin.
Side effects are uncommon but can include: increased drinking,
increased urination (PU/PD), vomiting, diarrhea, and inappetence.
Higher doses can induce sinus tachycardia (fast heart rate), and
ventricular arrhythmias. In an article on Pimobendan use in more
than 100 dogs (U of Georgia), found Pimobendan to be "virtually
free of overt adverse effects in dogs..." One dog did develop mild
diarrhea. Thus less than 1% developed mild diarrhea. That is a lot
safer than digoxin!
When Pimobendan becomes approved here in the US, it will be
become the drug of choice to use with an ACE inhibitor and lasix
for those moderate to severe dilated cardiomyopathy cases.
Jerry Murray, DVM
PS No, I do not work for the manufacturer (Boehringer Ingelheim),
and No, I do not own stock in that company.
[Non-text portions of this message have been removed]
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