From:
Marie Smith
Date: 2008-01-20 18:26:12 UTC
Subject: [ferrethealth] Tazz's report
To: ferrethealth@yahoogroups.com
Ok now, they are not to sure if he has cancer. Chemo is out of the question, what meds, herbal can I give him that is not tough on his liver.
As you can see they don't do many ferrets.
Thank You
[section naming vet, hospital, giving private contact info for same,
etc. removed as per rules]
Patient: TMZ SMITH
Age: 11Y Sex:M NeuteredY: Species: Ferret
[Removed]
Ferret Vet: [Removed as per rules]
EXPLORATORSYX :M ULTIPLEB IOPSIESE.N LARGEDS PLEENA, LLE LSEL OoKSN ORMAIV. ERYF MGILE IIVER& SPLEENB UT
[Looks like:
Multiple Biopsies enlarged spleen ????? then I can make out Liver and Spleen later]
MAYBET HAT'SN ORMALF ORA FERRETH. ISTOS OURCEL: IVERS, PLEENl,N T.,L ,N
[looks like Maybe that's normal for a ferret. Histo ???]
Tests Ordered:
;;,rlffiqlri;i*lli,;
Histology
BIO ML
r,,:::t:ll::l:: Normal ,, :. . out:of'Rabge-' ::, .Units iReieii-nchinrnia::r:;
Biopsym uftiple ACCESSIONN O.: 1071212105
HISTO NO.: [removed]
HOSPITAL: [Removed]
VETERINARIAN: {Removed]
OWNER: SMITH
ANIMAL: IAU
BIOPSYS ITE: SPLEEN,L IVER,I NTESTINEM, ESENTERICL YMPHN ODE
[Looks like Spleen, liver, intestine, node]
GROSS: Multiples urgicabl iopsieso f liver,s pleen,in testinea ndm esenlery
lymph node from this ferret were trimmed and sectioned.
HISTOLOGY:
There are subtlel esionsi n the llvera nd the intesline.W e are suspic-rouosf early
lymphomaT. herei s alsoa mildf ocalh epatitis.
[Looks like subtle lesions in the liver and intestine have them suspicious that there IS lymphoma, also mild focal hepatitis.]
There are three differentc hangesp resenti n the liver. The most obviousi s
markedv acuolationo f many hepalocytesw ith a tendencyf or the periportarl egions
lo be affected primarily. Mosl of the hepatocyles have a swollen and clear
cytoplasma nd only occasionacl ellsh ave distinctl ipidv acuoles.D ottedt hroughout
the parenchymao f the livera re smallc lusterso f neutrophilsa nd occasionadl ead
hepatocytes.T heser epresentle ssl han 17oo f the parenchymala rea.
There are numerouss malll ymphocytesa roundl he portalt riads. In some regions,
these lymphocytesa re uniformc ellsl hal are 20 cellst hick and arrangede qually
around artery, bile duct and vein. Some of lhe bile ducts are distended and
conlain bile.
[Description above is maybe 60% to 70% readable depending on sentence but with real difficulty usually. Ditto intestinal description below. It would be good if these were transcribed by hand by poster if time allows since not all vets and experienced readers may have the time to wade through.]
The sampleo f the smalli ntestinea lso has mulliplec hanges. Some of the crypts
appear to be blunled and the crypt lo villus ralro is increased and appears to be
between1 :1a nd 1,2. Someo f the viltia re fittedw ilh smalll ymphocytesa,n d
overallh ? cellularitoyf the laminap ropriais increasedb y a similarp opulationo f
cells. The tips of some villi,p articularlyth ose filledw ith lymphocytesh, ave marked
intraepithelially mphocytea ccumulations uch that, at leastt ocally,e pitheliacl ells
are obliterated. This change is so variable that some villi are normal. Other cells in
the laminap ropriaa re minimali n number.T he cryplsa re hyperplasticth roughout
and there are numerousm itosesi n the epithelialc ellsa t all levelso f lhe crypts.
There is a noduleo f mesentericfa t presento n one slide and that is normal.
MORPHOLOGICA/LA ETIOLOGICADLI AGNOSIS:
1. SUSPECTE ARLYS MALLC ELLL OW.GRADEIN TESTINALL YMPHOMA
WITH HEPATICI NVOLVEMENT.
2. HEPATICG LYCOGENOSIS.
3. MILD FOCAL HEPATITIS.
[The above says that there is suspected low grade intestinal lymphoma with liver involvement and liver changes as a result such as focal hepatitis.]
COMMENT:
The intestinacl hangesa re suspiciousfo r early lymphomaa nd the presenceo t
similarl ymphocytesin porlall riadsi s supportiveo f lhis. lt is possiblef or some
types of intestinarl eactivec hangest o producen urnerousl ymphocytesw ithint he
epithelium;h owever,t he numberp resenth ere is particularlye xaggerated.W e
assumet he presenceo f glycogeni n hepatocytesis a metabolicc hanget hat may
psdormsadt r epoial ddresusn lasso therwisneo tedL: angley(LC)a, lgary(CE)d. monron(VEln) couver(V)
[intestinal epithelial lymphoma, and people can puzzle out the rest]
Page1 o t?
[Removed same]
EXPLORATORSYX ;M ULTIPLBEI OPSIESE.N LARGEDS PLEENA, LLE LSEL OOKSN ORMALV. ERYF RAGITEL IVER8 SPLEENB UT
MAYBET HAT.SN ORMALF ORA FERRETH. TSTOS OURcE:L IVERS. PLEENI.N T..L .I,
iriT$fii!ir,r:::r,r: :':lirrf ;rrrrr,:rlr U qfr1f ,,;r..".,,,...:.rr,,,,,,....,Ooui,fn ruge t,,,, :, t,,,,:,i lU tS
be relatedto a lacko f dietarvin take.
[They appear to pointing out the changes to ferret livers that can happen from not eatting, as per
http://www.afip.org/ferrets/Clin_Path/ClinPath.html
and
http://www.afip.org/ferrets/PDF/Ferret_GI_path_reports.pdf
,..:"r',.:.;; ; pulu;.relRtbig! ::
'-
::i
Wew ishw e couldb eo f greatehr elpw ithc orrelalinogu rh istologicafiln dingws ith
thec linicahl istory.
PATHOLOGIST: Dr [Removed] osteBr VSCp, hD,M ACVSCO, iplomatAeC VP
Testp erfolmeadt Histovel
Comments:
Dr.[Removed]
Porformeda t r?porta ddressu nlegso th?rwii6n ot?d;L angley(L)c,a lgary(c),E dmonton(Ev)a ncouver(v)
page 2 ot z
BCMarie and her 4 Most Wonderful Fur Kidlets in BC
[Moderator's Note: This is really something of a mess; it looks like a scanner with poor recognition was used. Hopefully, people will be able to pull enough from it to help]
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