From:
"M. Michaela Maurice, DVM"
Date: 2008-02-16 02:16:09 UTC
Subject: [ferrethealth] ADV testing - Is this correct?
To: ferrethealth@yahoogroups.com
(cross posted to the adv list)
Hi all.
I'm wondering if you can help me out. I'm a little confused about
the current status of ADV testing (and some of the details)
Can anyone tell me if what I have found is correct, if I've missed
anything, and/or if my understanding needs some help :)
Here's what I have thusfar: (btw, Ab=antibody)
1. CIEP is no longer being done by United Vaccines.
Question: Is the "CEP" done by the Blue Cross Animal
Hospital essentially the same test as the CIEP that was done by United?
CIEP
detects the presence of antibodies - not the virus
and therefore cannot
tell if animal is viremic, a carrier,
or has eliminated the virus - just
detects exposure
2. IFA is no longer being done .
3. Avecon has an Ab - Elisa test - only detects actively replicating
ADV and ONLY ADV antibodies. (their claim..?truth/reality?)
4.
Avecon has a QuickCheck Ab Test -- detects antibodies -
Avecon site
states comparable sensitivity and specificity to the Elisa
Question1: Does the Quickcheck test detect antibody without regard for active replication?
Question
2: The Elisa info claims the test only binds to ADV antibodies,
but the
quickcheck info doesn't claim this - does this mean the quickcheck
doesn't bind only ADV antibodies but others as well?
(If so, how then is sensitivity and specificity comparable between the two?)
5. University of Georgia
is developing a different Elisa test - more sensitive than CIEP
which
detects non-replicating ADV (and a shorter- 4 hour time turn-around )
-
not yet commercially available.
6. DNA in situ -
for post or biopsy - is this commercially available? where?
7. PCR at the University of Georgia - is this commercially available?
If so..any website? (can't find one)..
Thanks for any help you might have,
Dr. Meesh
a.k.a. meesh, meeshmeesh, M. Michaela Maurice, D.V.M.
If one advances confidently in the direction of their dreams,
and endeavors to lead a life which they have imagined,
They will meet with a success unexpected in common hours.
Henry David Thoreau
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