From:
"Karen McCabe"
Date: 2008-02-29 10:15:19 UTC
Subject: [ferrethealth] Re: Propecia
To: ferrethealth@yahoogroups.com
According to Dr. Delaney's studies....
"lupron plus adrenalectomy led to slightly longer lives in the males;
females receiving lupron alone lived longer than females having
surgery. All ferrets who receive adrenalectomy need to concurrently
have hormonal suppression to live the longest, the difference in
surgical outcome was in the males since the prostate enlargement
frequently is the life-limiting factor in males, not the size of the
adrenal tumor itself."
"As 3 month lupron is exorbitantly expensive, and if the 30 day lupron
is fresh, frozen for no more than 1-3 months, and dosages are not
missed, there has been no "refractoriness" to it in the 10 years I
have been using this drug in ferrets on a monthly basis. Some ferrets
on the study received monthly lupron for nearly 4 years with
effectiveness until the tumor was beyond pituitary control."
"Note: at my clinic and the Washington Ferret Rescue none of our
lupron used is over 30 days from mixing and freezing - usually
considerably less time. We go through over 150 100 mcg doses a month.
We have not seen refractoriness or lack of effectiveness with this
drug even used for more than 3 years monthly."
Karen McCabe
--- In ferrethealth@yahoogroups.com, "Sukie Crandall" <sukie@...> wrote:
>
> Well, personal experiences certain can vary. Ours has been that
surgery by far the best.
>
> Lupron and related drugs do become less effective over time in
humans according to a past
> post from a biochemist who works in the field:
> http://ferrethealth.org/archive/SG16513
> I don't know if anyone has done studies on Lupron to see if that is
the case for ferrets but a
> life-long study on the related deslorelin is being done and I
suspect it will be noted whether
> that problem might exist in ferrets with that drug.
>
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