From:
"Karen McCabe"
Date: 2008-03-05 01:40:37 UTC
Subject: [ferrethealth] Re: Thyroid Tumor?
To: ferrethealth@yahoogroups.com
Reading through your post again Sukie (and will read through it
several times more to be sure I fully grasp it all). From what I've
quoted below, it seems likely that my Ruca (and Connor as well, I
would assume) may carry the MEN gene(s). If any doctor or researcher
is interested in Ruca's case I would be more then willing to share any
information I can with them.
Karen McCabe
http://www.cinnamonsprite.net
--- In ferrethealth@yahoogroups.com, "Sukie Crandall" <sukie@...> wrote:
>
> BEGIN QUOTE
> The observed similarities between the manifested neoplasms in this
ferret and MEN
> syndromes in humans are tantalizing but incomplete. The presence or
absence of other
> MEN-associated neuroendocrine lesions, such as pituitary tumor,
parathyroid cell
> adenoma, or mucosal neuromas, which would support further MEN
subclassification,
> could not be confirmed in this ferret. Likewise, the presence of a
RET or mos proto-
> oncogene mutation or mutation in the MEN-I gene in this ferret has
not been established.
> It is hoped that this report will stimulate further studies to
elucidate whether the ferret
> has a heritable form of MEN comparable to that documented in humans.
> END QUOTE
>
> Remember that since then MEN (Multiple Endocrinological Neoplasia, a
genetic variation)
> HAS been found in ferrets by a veterinary research team at UC Davis
which is being led by
> Dr. Michelle Hawkins. Further details on that research may be made
public this year,
> depending on the progress of the work.
>
> Dr. Bob Hawkins at U Pitt has found another potential genetic
contributor: p53.
> Variations make it difficult for the body to fight tumors.
Yahoo! Groups Links
<*> To visit your group on the web, go to:
http://groups.yahoo.com/group/ferrethealth/
<*> Your email settings:
Individual Email | Traditional
<*> To change settings online go to:
http://groups.yahoo.com/group/ferrethealth/join
(Yahoo! ID required)
<*> To change settings via email:
mailto:ferrethealth-digest@yahoogroups.com
mailto:ferrethealth-fullfeatured@yahoogroups.com
<*> To unsubscribe from this group, send an email to:
ferrethealth-unsubscribe@yahoogroups.com
<*> Your use of Yahoo! Groups is subject to:
http://docs.yahoo.com/info/terms/