Message Number: FHL4458 | New FHL Archives Search
From: Sukie Crandall
Date: 2008-04-04 21:56:56 UTC
Subject: [ferrethealth] abstract
To: fhl <ferrethealth@yahoogroups.com>, ferret-l@LISTSERV.FERRETMAILINGLIST.ORG

Parasitol Res. 2008 Apr 3 [Epub ahead of print]
Efficacy of imidacloprid 10%/moxidectin 1% (Advocate(R)/Advantage
Multitrade mark) against fleas (Ctenocephalides felis felis) on
ferrets (Mustela putorius furo).
Wenzel U, Heine J, Mengel H, Erdmann F, Schaper R, Heine S,
Daugschiess A.
Veterinary Practice Dr. Wenzel, Helenenstr. 26a, Leipzig, Germany.

Ferrets (Mustela putorius furo) are becoming increasingly popular as
pets and are kept in households with other pet animals such as dogs
and cats, from which they may catch flea infestations with the
predominant flea species Ctenocephalides felis. In this study, the
efficacy of imidacloprid/moxidectin spot-on (Advocate(R)/Advantage
Multitrade mark) was investigated in the therapy and prevention of
flea infestation in ferrets. Sixteen adult ferrets of varying weights
and ages and of both sexes were included. Ferrets were infested with
50 fleas each on days -7, -1, 7, 14, 21, and 28. On study day -6, the
animals were randomized into two groups based on body weight and flea
count. Each ferret allocated to group 1 was treated with 0.4 ml of
imidacloprid 10%/moxidectin 1% (Advocate(R)/Advantage Multitrade
mark). The ferrets in group 2 remained untreated. Flea counts were
performed by combing 24 to 48 h after infestation. The primary
efficacy criterion was the reduction in the number of fleas at each
time point post treatment compared to the ferrets in the untreated
control group. On day 1, the therapeutic efficacy was 100%. The
preventative efficacy was 100% at 1 and 2 weeks post treatment, and it
was >97% and >90% at 3 and 4 weeks post treatment. No local or
systemic side effects were observed in any of the ferrets treated.

PMID: 18386063 [PubMed - as supplied by publisher]



Sukie (not a vet)

Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html




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