From:
"Sukie Crandall"
Date: 2008-04-22 15:23:09 UTC
Subject: [ferrethealth] Re: selamectin
To: ferrethealth@yahoogroups.com
For what parasites was your ferret being treated?
What were the symptoms?
(For example, was the ferret being treated for possible
ectoparasites when adrenal disease may have been
causing fur loss and even anemia?)
How much is the ferret eating and drinking?
The med can at times cause GI upset and if the ferret
is not eating and drinking enough that will spiral.
What tests have been done? What are the CBC results?
The Chemistry Panel Results? Among other things it sure
would be good to get a blood glucose on this one since
diabetes is among the possibilities. Although rare in
ferrets diabetes does require prompt treatment with the
right meds. See Archives if blood work by vet indicates
this problem to see which types of insulin work best for
ferrets:
http://ferrethealth.org/archive/
More specific info is needed, really, please. Many things
can cause most of the symptoms you list. Thirst can be
caused by the loss of fluid from normal uses (dehydration,
having it go through too fast or back out too fast, being
diabetic, having heart disease causing fluid to pool in the
body rather than be used (ascites or edema), some types
of irritation, etc. The thirst is the sole semi-specific thing
there.
It is not unusual for ferrets of 5 years or older to have some
types of medical conditions going on in the background
I don't know how to finagle URLs that have %20 in them to
get them to work but
http://www.jarvm.com/articles/Vol5Iss3/Beck%2087-96.pdf
can be looked up from the name using Google or with the
search terms
selamectin +ferret +reaction
It is
Efficacy and Safety of Selamectin
(Stronghold=AE/Revolution=99) Used
Off-Label in Exotic Pets
Maggie Fisher, DVM, DiplEVPC1
Wieland Beck, DVM, DiplEVPC2
Melanie J. Hutchinson, DVM1
Intern J Appl Res Vet Med =95 Vol. 5, No. 3, 2007
What dosing was used? 18 mg/kg? Less? More?
Some notes from
http://canadasaferx.com/Pet_Medications/Cat___Dog/Heartworm_Preventative/Re=
volution
_Mauve_-_cat___dog___2_6kg___selemectin_/index.html
BEGIN QUOTED SEGMENTS
When should Revolution Mauve - cat/dog <2.6kg not be taken?
Do not use this medicine if your pet is allergic to any ingredient in this =
medicine.
What precautions should I follow when taking Revolution Mauve - cat/dog <2.=
6kg?
Before using this medicine, tell your veterinarian if your pet is pregnant =
or lactating or
suffers from any other health condition.
What special warning(s) should I be aware of when taking Revolution Mauve -=
cat/dog
<2.6kg?
Keep this medicine out of the reach of children and pets. For external use =
only. If
swallowed call a poison control center or doctor immediately for treatment =
advice.
What are the side effects of Revolution Mauve - cat/dog <2.6kg?
Most severe: N/A
Most common: N/A
Other: N/A
END QUOTED SEGMENTS
http://www.vetmedonline.com/Pharmacy.html#Revolution
BEGIN QUOTE
Revolution: Selemectin (Revolution) is a topical anthelmintic that is an e=
ffective
preventative for heartworm, fleas and ticks in dogs and cats. It may also =
be used to treat
ear mites and scabies mites. It is also labeled to control roundworms and =
hookworms
only in cats. Selemectin is labeled for use in cats and dogs 6 weeks and o=
lder. Side
effects are uncommon but include gastrointestinal upset and local skin irri=
tation.
END QUOTE
http://vetmedonline.com/Articles/FleaandTickPrevent.htm
BEGIN QUOTE
Selemectin (Revolution)
=B7 Newer generation flea, tick and heartworm control
=B7 Effective against roundworms and hookworms in cats (not dogs)
=B7 Can also be used to treat ear mites or scabies mites
=B7 Topical monthly application to small area of back
=B7 Labeled for use in dogs and cats 6 weeks and older
=B7 Safe
o Blocks neurotransmitters found peripherally in parasites but not pe=
ripherally in
mammals
o Has been shown to be safe for collies and shelties also
o Side effects are limited but include skin irritation or vomiting
=B7 Some systemic absorption leads to resistance to bathing
END QUOTED SEGMENT
Side effects (dogs and cats) when heartworm is already present can be found
in:
http://72.14.205.104/search?
q=3Dcache:D_TLVm5v0wkJ:rover.vetmed.lsu.edu/student/2009/Heartworms.ppt+Sel=
emectin
+%2BFERRET%2Bside+effects&hl=3Den&ct=3Dclnk&cd=3D1&gl=3Dus&client=3Dsafari
or if it works for you:
rover.vetmed.lsu.edu/student/2009/Heartworms.ppt
and if that is a possibility check also the work of Dr. Deborah Kemmerer
(and she may well have also done later work on the topic after
marriage in which case also look up Dr. Deborah Kemmerer Cottrell, and Dr
Deborah Cottrell) such as
http://www.miamiferret.org/fhc/heartworm.htm
and also
http://www.heartwormsociety.org/
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
--- In ferrethealth@yahoogroups.com, "bn_bnt" <bn_bnt@...> wrote:
>
> I have used selamectin on my ferret. Is there a remote chance that the
> product had an adverse effect? It may be pure conincident but appr. a
> week later he became very ill. Now two weeks have passed since I
> applied the medication and he is just holding on. Our vets have next
> to no experience with ferrets, the one I took him to admitted he is
> the first ferret he seen for a long time.
>
> I know that selamectin should be used on healthy ferrets only. He
> appeared to be healthy at the time of treatment, but a condition
> unnoticed may have been made worse.
>
> He is five years old and may have an adrenal problem, the emphasis is
> on 'may'. Now he is losing weight, condition, is thirsty and must be
> fingerfed to eat at all. Sleeps a lot but when awake he is alert.
>
> Does anyone have any thoughts on that?
>
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